ID   T1PDK2_MUSDO            Unreviewed;       391 AA.
AC   T1PDK2;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Lipase {ECO:0000313|EMBL:AFP61403.1};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|EMBL:AFP61403.1};
RN   [1] {ECO:0000313|EMBL:AFP61403.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ALHF {ECO:0000313|EMBL:AFP61403.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:AFP61403.1};
RA   Liu N., Zhang L., Li M., Reid W.;
RT   "Transcriptome of adult Musca domestica launches a platform for comparative
RT   house fly gene expression and characterization of differential gene
RT   expression among resistant and susceptible house flies.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
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DR   EMBL; KA646774; AFP61403.1; -; mRNA.
DR   AlphaFoldDB; T1PDK2; -.
DR   VEuPathDB; VectorBase:MDOA007622; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd00707; Pancreat_lipase_like; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013818; Lipase.
DR   InterPro; IPR033906; Lipase_N.
DR   InterPro; IPR000734; TAG_lipase.
DR   PANTHER; PTHR11610:SF149; FI01450P-RELATED; 1.
DR   PANTHER; PTHR11610; LIPASE; 1.
DR   Pfam; PF00151; Lipase; 1.
DR   PRINTS; PR00821; TAGLIPASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   2: Evidence at transcript level;
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..391
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004583153"
FT   DOMAIN          93..365
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
SQ   SEQUENCE   391 AA;  42564 MW;  CAE62E60C851AE6E CRC64;
     MKLFVLCAIL GLCCLPNVQS LDLSFKNIVT STADVTTGVI KDVGNKLPTP QGLFETSKQL
     VAGYPFEFVS SAVNQLCASA LSSNAITPKI SPNIDKMFFQ LRTACNRYSH PLLKANEMWA
     SPEFDPKKKV VILATGWTTT VNETDTIDVF AKAYACRGDV NFVAIDAGSF VDTLYTWSAF
     NTEELGMHIA KGLEQLEKIV PLKNIHLIGH SLGAHIMGAA ARYFFERTGK LIPRVTGLDP
     AKPCFNEGEA LSGLMRGDAE FIDVIHSNSG VLGKRNPTGD VDFYPGGLDP LPPGCISVTC
     AHARAWEYFA ETIYPGNENN FLGARCTSLT RLREHKCPKQ DVPMGYAAPT NIKGSYFMEV
     RGEAPFGMRG DKTRSLANDQ CGKCPDATKK A
//