ID T1PLM2_MUSDO Unreviewed; 776 AA.
AC T1PLM2;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=SH3 domain protein {ECO:0000313|EMBL:AFP64311.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EMBL:AFP64311.1};
RN [1] {ECO:0000313|EMBL:AFP64311.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ALHF {ECO:0000313|EMBL:AFP64311.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:AFP64311.1};
RA Liu N., Zhang L., Li M., Reid W.;
RT "Transcriptome of adult Musca domestica launches a platform for comparative
RT house fly gene expression and characterization of differential gene
RT expression among resistant and susceptible house flies.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KA649682; AFP64311.1; -; mRNA.
DR AlphaFoldDB; T1PLM2; -.
DR VEuPathDB; VectorBase:MDOA004940; -.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd11781; SH3_Sorbs_1; 1.
DR CDD; cd11782; SH3_Sorbs_2; 1.
DR CDD; cd11780; SH3_Sorbs_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR PANTHER; PTHR14167:SF114; CAP, ISOFORM AC; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 2.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 2: Evidence at transcript level;
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 197..260
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 517..576
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 589..648
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 717..776
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 776 AA; 88451 MW; 5806E3CE995A30CE CRC64;
MFTPKFKAKA ATGSGIWSPK NQTPSSSTSN LSEIKSTPPT PPPPPASSSS VIWTPQQSPQ
LGRKEYRPVR FESPTPRRRI QSTSSEPPLP PWNNLTNNNF QSPNSCTNLS TPTSTVASEQ
DSTGSISLPG RSTSVSDKIK TFERSASATE LYTRPHNKRP HDKARPFCRP NEVIYNVKHE
YMSEPETEND RPRKMAQLGR RQYDGIGPMT TDGMPIILRS EVKEPHQHEW YKRLYQTIHK
QKHGDDYVIR YKYPRGRTQA KSNGYQSEPE PCYDSDYSVI KYRPVNTQRL QSVSSALNVR
SSNDKLYGTL PNPVKSEQNT YKNQPGRIED YVTGHSSISE KETKKQLDQA KLSSRYTEGN
LSRALAKESG YTSDSNLILH KKEIPPNSPL SPQEQKQAYK YVQAGGEPPL FGFRKAAPEK
SKVSPNRYYE SDVNIHFKTP VRQELKSPLS EEELALRQAQ QMQKLYQEER RRKYLQELQD
MNSRRHTDNF TPSQKSPIPL NRYDDFPADL APKNLSQIKS VARALYNFQA QNSKELSFKK
GDIIYIRRAI DKNWYEGEHN AMIGLFPANY VEIVNRDINQ PQQAPRSKPS EGQARAKYNF
QAQSAVELSL NKGELVALTR RVDDNWFEGR IANRKGIFPV SYVEVLTDIG AEDIAAKTTT
VQQTSTVNYR PSLDALRTNI NNEFNTLTRN GVQPPNSILR ETRPDHKIDI LHVDTSSEPL
VYRALYKYRP QNSDELELLE GDIVHVLEKC DDGWYVGTSQ RTGCFGTFPG NYVERL
//
