ID   T1UBZ0_HELPX            Unreviewed;       894 AA.
AC   T1UBZ0;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=DEAD/DEAH box helicase family protein {ECO:0000313|EMBL:AGT73933.1};
GN   ORFNames=HPSA20_0696 {ECO:0000313|EMBL:AGT73933.1};
OS   Helicobacter pylori SouthAfrica20.
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=1352356 {ECO:0000313|EMBL:AGT73933.1, ECO:0000313|Proteomes:UP000015920};
RN   [1] {ECO:0000313|EMBL:AGT73933.1, ECO:0000313|Proteomes:UP000015920}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SouthAfrica20 {ECO:0000313|EMBL:AGT73933.1};
RX   PubMed=24072860;
RA   Duncan S.S., Bertoli M.T., Kersulyte D., Valk P.L., Tamma S., Segal I.,
RA   McClain M.S., Cover T.L., Berg D.E.;
RT   "Genome Sequences of Three hpAfrica2 Strains of Helicobacter pylori.";
RL   Genome Announc. 1:e00729-13(2013).
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DR   EMBL; CP006691; AGT73933.1; -; Genomic_DNA.
DR   AlphaFoldDB; T1UBZ0; -.
DR   KEGG; hpys:HPSA20_0696; -.
DR   PATRIC; fig|1352356.3.peg.682; -.
DR   HOGENOM; CLU_002151_0_0_7; -.
DR   Proteomes; UP000015920; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd18785; SF2_C; 1.
DR   Gene3D; 3.40.1350.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR039442; Mrr-like_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR011856; tRNA_endonuc-like_dom_sf.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF13156; Mrr_cat_2; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:AGT73933.1};
KW   Helicase {ECO:0000313|EMBL:AGT73933.1};
KW   Hydrolase {ECO:0000313|EMBL:AGT73933.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:AGT73933.1}.
FT   DOMAIN          188..389
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          489..655
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          676..703
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   894 AA;  102070 MW;  C16483D826811E4C CRC64;
     MSEINTYKLI KEKLQAIPNQ RRKGSLFEKV CKRFLEEHDS ANEYESIKLW SDWELRGNKS
     DCGIDMVIQT TSKEYIAVQC KFHQDSVSFN ELSTFFTQLL SGVGEIRFKK GIIITTSNLS
     ANAQQAIEQI RSTGMGIDID EINEEDFIYS RIDWEKFDPA QTQGELPLCD KKRPHPHQTE
     AIEKTKEYFS DPKNARGKLI MACGTGKTYT SLKIMESLEP KIMLFLAPSI ALLSQTFREY
     AQEKSEPFYA SIVCSDDKVG KSKNEDNDDI NFSELPLKPS TRLEDILSVY EKAKQENKRF
     IIFSTYQSAL RIKEAQERGL DKIDLMICDE AHRTVGAMFS TNERDDKNAF TLCHSDENIK
     AQQRLYMTAT PKVYSEDSQT KAKESGNLVY SMDDADIFGE EIYTLNFEKA IALDLLTDYK
     VIILAVRSEN LSGVTNSVNK KISQLNAEGT KLDKKLINNE FVCKIIGTHK GLAKQDLIAL
     DDENKEDNDL QDKTDTIPSK RAISFCKSIK TSKNIKDSFQ TIIECYDEEL KKKSFKNLEI
     SIDHIDGTMN CKVRLDKLET LNQPEQNTCK VLSNARCLSE GVDVPALDSI VFFDGKSAMV
     DIIQAVGRVM RKAKGKKRGY IILPIALEES EIKNLNEAIN NTNFKNIWKV LKALRSHDSR
     LVDEATFREK IKVFGSDDGS NTDDEELDEE SQKDKNEPNE KSKQAQKTLF DAIFLQDLAN
     AMYNVMPTKL GDRNYWENFA KKTGSIARTL NKCLNALFDK NPEIFQNFLT SLRENIHQNI
     KEDEALDMIV SHIITKPIFD AIFGENIKNP IPKALDKMVL KLSDLGLEGE TKDLKNLYES
     VKTEAARAKS QKSQQELIKK PLQHFFKNRF QKTERKTRDR LYAYGSGGFH FKSH
//