ID T2BP28_CRYNH Unreviewed; 465 AA.
AC T2BP28;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Kelch repeat-containing protein, variant {ECO:0000313|EMBL:AGV15304.1};
GN ORFNames=CNAG_00392 {ECO:0000313|EMBL:AGV15304.1};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AGV15304.1, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AGV15304.1, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
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DR EMBL; CP003820; AGV15304.1; -; Genomic_DNA.
DR RefSeq; XP_012046688.1; XM_012191298.1.
DR AlphaFoldDB; T2BP28; -.
DR GeneID; 23884200; -.
DR VEuPathDB; FungiDB:CNAG_00392; -.
DR HOGENOM; CLU_019536_3_0_1; -.
DR OrthoDB; 201813at2759; -.
DR Proteomes; UP000010091; Chromosome 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR23244; KELCH REPEAT DOMAIN; 1.
DR Pfam; PF01344; Kelch_1; 4.
DR Pfam; PF13854; Kelch_5; 2.
DR SUPFAM; SSF117281; Kelch motif; 2.
PE 4: Predicted;
FT REGION 1..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 465 AA; 51355 MW; E91B3026D9CD180F CRC64;
MTHPGALSRN LPEASLPRSD PESSDSTRKS TSVPSANADA AAARRLPAHP SGLHASRTDP
CTPAGELDNA YEQTAARRRR AGTRSERPST QPNTDSKGQR TYSRTAYPRK PLEPRLPSAK
NVPRAPASSM YFSPVPCYGF PPNQALRAHT GTLVGERIWV IGGVDKQTCF RDVACFDTES
FMWSILETQG EHFPPLRAHT TTLVGDKLFI FGGGDGPSYS NDVWILDTTT HRFSRPSFSP
DLPLPPPRRA HSTVLYQHYL IVFGGGNGQA ALNDVWALDV SDPNALTWTE WKTRGDIPQK
KGYHTANLIG DKMVVFGGSD GHASFADVHV LNLKTCVWTL INTDIKHNRL SHTSTQVGSY
LFVIGGHNGQ AYAQDVLLFN LVTLQWEVKL PRGIFPPGRG YHVALLHDAR IFLSGGYNGE
TVFDDFWILD LSASAYLPQV TTFQVDENLY ERSITEPSSL WQNRL
//
