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Database: UniProt
Entry: T2I4B7_9BURK
LinkDB: T2I4B7_9BURK
Original site: T2I4B7_9BURK 
ID   T2I4B7_9BURK            Unreviewed;       329 AA.
AC   T2I4B7;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=Protein RecA {ECO:0000256|ARBA:ARBA00015553, ECO:0000256|RuleBase:RU000526};
DE   AltName: Full=Recombinase A {ECO:0000256|RuleBase:RU000526};
DE   Flags: Fragment;
GN   Name=recA {ECO:0000313|EMBL:CCL97755.1};
OS   Burkholderia metallica.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=488729 {ECO:0000313|EMBL:CCL97755.1};
RN   [1] {ECO:0000313|EMBL:CCL97755.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Type strain: LMG 24068 {ECO:0000313|EMBL:CCL97755.1};
RX   PubMed=23867250; DOI=10.1016/j.syapm.2013.06.003;
RA   Peeters C., Zlosnik J.E., Spilker T., Hird T.J., Lipuma J.J., Vandamme P.;
RT   "Burkholderia pseudomultivorans sp. nov., a novel Burkholderia cepacia
RT   complex species from human respiratory samples and the rhizosphere.";
RL   Syst. Appl. Microbiol. 0:0-0(2013).
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage. {ECO:0000256|ARBA:ARBA00025580}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000256|ARBA:ARBA00009391,
CC       ECO:0000256|RuleBase:RU004527}.
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DR   EMBL; HE981733; CCL97755.1; -; Genomic_DNA.
DR   AlphaFoldDB; T2I4B7; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   CDD; cd00983; RecA; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   HAMAP; MF_00268; RecA; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049261; RecA-like_C.
DR   InterPro; IPR049428; RecA-like_N.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR023400; RecA_C_sf.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   NCBIfam; TIGR02012; tigrfam_recA; 1.
DR   PANTHER; PTHR45900:SF1; MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR45900; RECA; 1.
DR   Pfam; PF00154; RecA; 1.
DR   Pfam; PF21096; RecA_C; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF54752; RecA protein, C-terminal domain; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004527};
KW   DNA damage {ECO:0000256|RuleBase:RU004527};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172,
KW   ECO:0000256|RuleBase:RU004527}; DNA repair {ECO:0000256|RuleBase:RU000526};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004527};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004527};
KW   SOS response {ECO:0000256|RuleBase:RU000526}.
FT   DOMAIN          36..195
FT                   /note="RecA family profile 1"
FT                   /evidence="ECO:0000259|PROSITE:PS50162"
FT   DOMAIN          200..273
FT                   /note="RecA family profile 2"
FT                   /evidence="ECO:0000259|PROSITE:PS50163"
FT   NON_TER         329
FT                   /evidence="ECO:0000313|EMBL:CCL97755.1"
SQ   SEQUENCE   329 AA;  35424 MW;  FDE0943E24D9BB1C CRC64;
     MTAEKSKALA AALAQIEKQF GKGSIMRMGD AEAAENIQVV STGSLGLDIA LGVGGLPRGR
     VVEIYGPESS GKTTLTLQVI AELQKLGGTA AFIDAEHALD VQYAAKLGVN VPELLISQPD
     TGEQALEITD ALVRSGSIDM IVIDSVAALV PKAEIEGEMG DSLPGLQARL MSQALRKLTG
     TIKRTNCLVI FINQIRMKIG VMFGNPETTT GGNALKFYSS VRLDIRRIGS IKKNDEVIGN
     ETRVKVVKNK VSPPFREAIF DILYGEGISR QGEIIDLGVQ AKIVDKAGAW YSYNGEKIGQ
     GKDNAREFLR ENPEIAREIE NRIRESLGV
//
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