ID   T2M284_HYDVU            Unreviewed;      1575 AA.
AC   T2M284;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   22-FEB-2023, entry version 21.
DE   SubName: Full=Protein FAM179B {ECO:0000313|EMBL:CDG66353.1};
GN   Name=FAM179B {ECO:0000313|EMBL:CDG66353.1};
OS   Hydra vulgaris (Hydra) (Hydra attenuata).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Aplanulata; Hydridae; Hydra.
OX   NCBI_TaxID=6087 {ECO:0000313|EMBL:CDG66353.1};
RN   [1] {ECO:0000313|EMBL:CDG66353.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole animals {ECO:0000313|EMBL:CDG66353.1};
RX   PubMed=24065732; DOI=10.1093/gbe/evt142;
RA   Wenger Y., Galliot B.;
RT   "Punctuated emergences of genetic and phenotypic innovations in eumetazoan,
RT   bilaterian, euteleostome, and hominidae ancestors.";
RL   Genome Biol. Evol. 5:1949-1968(2013).
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DR   EMBL; HAAD01000121; CDG66353.1; -; mRNA.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024395; CLASP_N_dom.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR21567; CLASP; 1.
DR   PANTHER; PTHR21567:SF87; CRESCERIN-LIKE PROTEIN CHE-12; 1.
DR   Pfam; PF12348; CLASP_N; 1.
DR   SMART; SM01349; TOG; 3.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   2: Evidence at transcript level;
FT   DOMAIN          262..489
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          1067..1299
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          1343..1561
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REGION          910..936
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1297..1338
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        915..936
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1297..1321
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1322..1338
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1575 AA;  177163 MW;  45D379C3860A5E2C CRC64;
     MIPSVLEFES SHKFQGCNGF DTESKRVSFL EKVQESLKRT GGRLVYDKPL DLIYVLNQAL
     YDELPHTRCI AMTILIDAIP LYGMELDNHL KLLFPGILDN LVNRNLPVKR CALQVLHLYF
     KRNADKSLII DSLLRHGFTN SNKVLRNEVF LIVPALVRSG FNKKDLKELF VSVLKILPQI
     DVAESKLPVL LCLEHIKDSI GEEFTSFLTS LEKNLIDSYN NIMLKTSFSR KENIISRGKL
     IAVNESPNFK ESFHVENKLS CDLLFGFLPQ TVMDKLNNRA SLEDRSYACN EFIKHLSSAE
     VILVQSNAES ILEIISTLLV ESDLSVALPA LSLLHRLITI IGHSVKEHLN ILTNLMLKIM
     NDPRAVLRKL NLCIGLTVMH NLSPDVFFQN IIPHLFNKSA RVREEIINMI IGGLLTFPAS
     SFNLKQLPSQ ITFCLLDKKK RVRHACLECL AVLAHSLGSG HLKPLVLAVD NLESQYEGVL
     AAVQARLSRS LLPSINEEGL IQYALVIPSN VDKMVCHLPD VAWILSGTVV NNHNNYESQL
     HSNSSAIKSH LHKHNGIEDT NLQFVSQRSA VVRSAPVYQI SNEVVDHKLS DLLTTRNLKQ
     KQSEKNKSFE NDLDNDQAFL RSESNSSYFE MYKTKMKQIK AAGLQADINV LQNVLPMNNR
     SNFHSPEMLK NTLKIEPYSR SFVTSPNFNI SPVNCGVSLS PLGFLSTGRS NAHSDKQDHD
     QQIPIKPTLV RSASSKRNTS ASLKKEDLLQ VDDLAHTLPK CRSQLRRISG IMDSPFPLRP
     TIHRTPSGRM SGKCVFEIEH QSDSSNLENM KMLSISSPAI TDNAFTQEIT SEKDIIFDRN
     MKSPFIKTPK ARVMKSPINS IKNETDFTDR KYFKNSTDQS LKMQSAFQDN NNNTASFDTD
     SVDNQGFIKS SSVKKARSKN HDLSKQDQKL HKKHKGKIEQ QELRMQEEVR LWKESEEQRK
     EEDKKYILED IKKSYVVKKV PKTKERIEIK DVSDACIENL DEQIDLRRSV EKKDFSNNLN
     CLNTSLDSPD SSGFIAQTKN TSRKSLQVIE NQLVTRDLPS CSPVECKVDE PDTLQNNVSS
     ITIALQLLKS SQEEWENKCE GITMVRQLLR THQDAVIGQF HLVVEAVLNE VKNLRSQVTR
     AALGCVAELF EYVPKMAESE TEVILKGILQ KAADTNQFIR QDVDTVMTYF VANINPVKAV
     SALIAFGTSH RNGQIRKICA KAMADIAEKI GYSRLLSIHK DILVVSAKLA TDSQQDSRYH
     GRRILNCLLD CPDLDKLIVK DLPKANIIAV QEGLGEPPTG SATSRVLQSS SGLSPTKSSK
     IRAQHISHEE DNSRLTQRKK KTRLKELTDV GKAIDMDSLQ KLESANWNER YSGLDDFYNL
     VSMNPTAVSA QVVKIFDKFS PRLCDSNSKV SLYALQILNR CIPILRNGIS PAATILVENL
     KTLLASKNDT IFSAAKDCMV SLTKLVDNNT LVLPLATAVQ YSNSRNRAEL TDLLNDIIPT
     VFARKPGTIH RVILPVLWKL LAMPYSNESS PGHISMQEAL VKFIHTLYDC IGIELKNEAA
     TKEPIILQRI EELIG
//