ID T2M3C3_HYDVU Unreviewed; 294 AA.
AC T2M3C3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Mortality factor 4-like protein 1 {ECO:0000313|EMBL:CDG66773.1, ECO:0000313|RefSeq:XP_012554923.1};
GN Name=MORF4L1 {ECO:0000313|EMBL:CDG66773.1};
GN Synonyms=LOC100197355 {ECO:0000313|RefSeq:XP_012554923.1};
OS Hydra vulgaris (Hydra) (Hydra attenuata).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6087 {ECO:0000313|EMBL:CDG66773.1};
RN [1] {ECO:0000313|EMBL:CDG66773.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Whole animals {ECO:0000313|EMBL:CDG66773.1};
RX PubMed=24065732; DOI=10.1093/gbe/evt142;
RA Wenger Y., Galliot B.;
RT "Punctuated emergences of genetic and phenotypic innovations in eumetazoan,
RT bilaterian, euteleostome, and hominidae ancestors.";
RL Genome Biol. Evol. 5:1949-1968(2013).
RN [2] {ECO:0000313|RefSeq:XP_012554923.1}
RP IDENTIFICATION.
RC STRAIN=105 {ECO:0000313|RefSeq:XP_012554923.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; HAAD01000541; CDG66773.1; -; mRNA.
DR RefSeq; XP_012554923.1; XM_012699469.1.
DR EnsemblMetazoa; XM_012699469.1; XP_012554923.1; LOC100197355.
DR GeneID; 100197355; -.
DR KEGG; hmg:100197355; -.
DR OMA; GLQTYFD; -.
DR OrthoDB; 2878816at2759; -.
DR Proteomes; UP000694840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd18983; CBD_MSL3_like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.274.30; MRG domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR008676; MRG.
DR InterPro; IPR038217; MRG_C_sf.
DR InterPro; IPR026541; MRG_dom.
DR InterPro; IPR025995; Tudor-knot.
DR PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR10880:SF48; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05712; MRG; 1.
DR Pfam; PF11717; Tudor-knot; 1.
DR PIRSF; PIRSF038133; HAT_Nua4_EAF3/MRG15; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS51640; MRG; 1.
PE 2: Evidence at transcript level;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000694840};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 24..80
FT /note="Chromo"
FT /evidence="ECO:0000259|SMART:SM00298"
FT REGION 72..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 294 AA; 34577 MW; 1F116AF77F602822 CRC64;
MAPANEKKKF IDGEKVLCYH GPLLYEAKIV KTRTKDRVTK YLIHYAGWNV KWDEWAAESR
VMKYNEEGLK KQKELKHHHS NAKKSKNKNA KDEKKDESTS TQSKKRKGRG VNAESEPSYV
QKLDVKVIVP QDLRRYLLDD CDFVTRQRQL VPLPKPPGFS VKDITEKYLK YKVETTNDLK
NYSSLVEVCN GLCEYFDVMI GSQLLYKFER TQYSDLLKEY PNKPLSELYG CEHFLRLCIM
LGNVLSYSCL DESSMEFVVM HIHDFLDFMM RNSEDFFVAE YENSTPDYQR RCAF
//
