ID T2M657_HYDVU Unreviewed; 417 AA.
AC T2M657;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Galactose-3-O-sulfotransferase 2-like {ECO:0000313|RefSeq:XP_002169884.2};
DE SubName: Full=Galactosylceramide sulfotransferase {ECO:0000313|EMBL:CDG67768.1};
GN Name=GAL3ST1 {ECO:0000313|EMBL:CDG67768.1};
GN Synonyms=LOC100206557 {ECO:0000313|RefSeq:XP_002169884.2};
OS Hydra vulgaris (Hydra) (Hydra attenuata).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6087 {ECO:0000313|EMBL:CDG67768.1};
RN [1] {ECO:0000313|EMBL:CDG67768.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Whole animals {ECO:0000313|EMBL:CDG67768.1};
RX PubMed=24065732; DOI=10.1093/gbe/evt142;
RA Wenger Y., Galliot B.;
RT "Punctuated emergences of genetic and phenotypic innovations in eumetazoan,
RT bilaterian, euteleostome, and hominidae ancestors.";
RL Genome Biol. Evol. 5:1949-1968(2013).
RN [2] {ECO:0000313|RefSeq:XP_002169884.2}
RP IDENTIFICATION.
RC STRAIN=105 {ECO:0000313|RefSeq:XP_002169884.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the galactose-3-O-sulfotransferase family.
CC {ECO:0000256|ARBA:ARBA00008124}.
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DR EMBL; HAAD01001536; CDG67768.1; -; mRNA.
DR RefSeq; XP_002169884.2; XM_002169848.3.
DR EnsemblMetazoa; XM_002169848.3; XP_002169884.2; LOC100206557.
DR EnsemblMetazoa; XM_002169848.4; XP_002169884.2; LOC100206557.
DR GeneID; 100206557; -.
DR KEGG; hmg:100206557; -.
DR OMA; EVQYMAR; -.
DR OrthoDB; 3032344at2759; -.
DR Proteomes; UP000694840; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0001733; F:galactosylceramide sulfotransferase activity; IEA:InterPro.
DR GO; GO:0009247; P:glycolipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR009729; Gal-3-0_sulfotransfrase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR14647; GALACTOSE-3-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR14647:SF63; PUTATIVE-RELATED; 1.
DR Pfam; PF06990; Gal-3-0_sulfotr; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000694840};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:CDG67768.1}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..417
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041199706"
SQ SEQUENCE 417 AA; 49304 MW; 44776927A03D34D0 CRC64;
MRSFSKTKLL CFVASLSVIL LTSRILPSFQ PSLIRITKAN QGFLSKKNSS LNKRSCIPKK
NVVFLKTHKT GGSTITNILN RFGESRRLTF ILPKLGENRL DWPWFFRKDS FYPLNGSTPN
ILNNHARYNP DVMQEIMPND TVYITIVRNP ITQFESSFSY MTFDKILGMQ NSTDPLEEFF
KNPEQVLVNY VLTQDLRINS DRLKLIRNGM FYDLGLESKD FKNQKKIRSS IEKLDSQFDL
VMITEYFEES LVLLKRLMCW EIDDVVFFRL KQRSNELKRT ISKSLQKKIM QWSQADVQLY
KHFNRTFWTV LKNIGKDFWD EVNLLKAKNK IMSDLCLQQM NQVSSELFQT VQTKQYKLRT
NIPYSTREMC KRMTWDEIKY VKHLRELQTS KDEKKDSNGI LLKATAWLTN QLHFYLI
//
