ID T5AF07_OPHSC Unreviewed; 392 AA.
AC T5AF07;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Translocation protein SEC62 {ECO:0000256|ARBA:ARBA00021257};
GN ORFNames=OCS_03965 {ECO:0000313|EMBL:EQL00322.1};
OS Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba
OS caterpillar fungus) (Hirsutella sinensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=911162 {ECO:0000313|EMBL:EQL00322.1, ECO:0000313|Proteomes:UP000019374};
RN [1] {ECO:0000313|EMBL:EQL00322.1, ECO:0000313|Proteomes:UP000019374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Co18 / CGMCC 3.14243 {ECO:0000313|Proteomes:UP000019374};
RC TISSUE=Fruit-body {ECO:0000313|EMBL:EQL00322.1};
RX DOI=10.1007/s11434-013-5929-5;
RA Hu X., Zhang Y., Xiao G., Zheng P., Xia Y., Zhang X., St Leger R.J.,
RA Liu X., Wang C.;
RT "Genome survey uncovers the secrets of sex and lifestyle in caterpillar
RT fungus.";
RL Chin. Sci. Bull. 58:2846-2854(2013).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SEC62 family.
CC {ECO:0000256|ARBA:ARBA00010604}.
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DR EMBL; KE652846; EQL00322.1; -; Genomic_DNA.
DR AlphaFoldDB; T5AF07; -.
DR eggNOG; KOG2927; Eukaryota.
DR HOGENOM; CLU_040936_0_0_1; -.
DR Proteomes; UP000019374; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR004728; Sec62.
DR InterPro; IPR011553; Sec62_asco.
DR NCBIfam; TIGR00869; sec62; 1.
DR PANTHER; PTHR12443; TRANSLOCATION PROTEIN SEC62; 1.
DR PANTHER; PTHR12443:SF9; TRANSLOCATION PROTEIN SEC62; 1.
DR Pfam; PF03839; Sec62; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000019374};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 253..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 392 AA; 44797 MW; 66319FC5ACE739C9 CRC64;
MPGKPPPPGQ MPPGMQRPTP EQMAEIQRRV TEDAQKAGMT VPEFIEHIKR QATEQQRMRM
QQQSEDHDHD HCDCGHDHDH DHDHDHDHDH DHDHDHDHEH GPNCDHDHHH SQSQPINPGP
PNPKALAVAK FLKGQDLKPR TCILNGERKD MFKSKWSKAS LGWSPARSPA YEKARKKNPL
LPEINDRASL ENTFKLLPLS MLALRVSKID TDSSKKAKRV KGQWTVRIEQ QQEAKDEMYY
AWLWEGSQIK RQLYAALALL VIFIIVLYPL WPLKLRQGVY YLSWGLLGLL GLFFLMAIFR
VILFCITYFA VSPGLWLYPN LWEDVSFMDS FRPVWAWHET AEEKKLKKKS KKRSKVAASG
GGTNATFAAA TGQVAPTTAT TTGTDTQIQT HP
//
