ID   T5AJ61_OPHSC            Unreviewed;       351 AA.
AC   T5AJ61;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=pyridoxal kinase {ECO:0000256|ARBA:ARBA00012104};
DE            EC=2.7.1.35 {ECO:0000256|ARBA:ARBA00012104};
GN   ORFNames=OCS_02497 {ECO:0000313|EMBL:EQL01797.1};
OS   Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba
OS   caterpillar fungus) (Hirsutella sinensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=911162 {ECO:0000313|EMBL:EQL01797.1, ECO:0000313|Proteomes:UP000019374};
RN   [1] {ECO:0000313|EMBL:EQL01797.1, ECO:0000313|Proteomes:UP000019374}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Co18 / CGMCC 3.14243 {ECO:0000313|Proteomes:UP000019374};
RC   TISSUE=Fruit-body {ECO:0000313|EMBL:EQL01797.1};
RX   DOI=10.1007/s11434-013-5929-5;
RA   Hu X., Zhang Y., Xiao G., Zheng P., Xia Y., Zhang X., St Leger R.J.,
RA   Liu X., Wang C.;
RT   "Genome survey uncovers the secrets of sex and lifestyle in caterpillar
RT   fungus.";
RL   Chin. Sci. Bull. 58:2846-2854(2013).
CC   -!- SIMILARITY: Belongs to the pyridoxine kinase family.
CC       {ECO:0000256|ARBA:ARBA00008805}.
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DR   EMBL; KE652419; EQL01797.1; -; Genomic_DNA.
DR   AlphaFoldDB; T5AJ61; -.
DR   eggNOG; KOG2599; Eukaryota.
DR   HOGENOM; CLU_046496_0_0_1; -.
DR   Proteomes; UP000019374; Unassembled WGS sequence.
DR   GO; GO:0008478; F:pyridoxal kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0009443; P:pyridoxal 5'-phosphate salvage; IEA:InterPro.
DR   CDD; cd01173; pyridoxal_pyridoxamine_kinase; 1.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR013749; PM/HMP-P_kinase-1.
DR   InterPro; IPR004625; PyrdxlKinase.
DR   InterPro; IPR029056; Ribokinase-like.
DR   NCBIfam; TIGR00687; pyridox_kin; 1.
DR   PANTHER; PTHR10534; PYRIDOXAL KINASE; 1.
DR   PANTHER; PTHR10534:SF2; PYRIDOXAL KINASE; 1.
DR   Pfam; PF08543; Phos_pyr_kin; 1.
DR   SUPFAM; SSF53613; Ribokinase-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:EQL01797.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019374};
KW   Transferase {ECO:0000313|EMBL:EQL01797.1}.
FT   DOMAIN          118..253
FT                   /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT                   /evidence="ECO:0000259|Pfam:PF08543"
SQ   SEQUENCE   351 AA;  37892 MW;  6439C5879C32CF93 CRC64;
     MTAGPPVLAT RVLAVASHVV SGYVGNKVAV FVLQSLGCDV AALNTVHFSN HTGYRQWTGT
     KASAQEIADI YRGLSQSFLD DFDMMLSGYI PGAEAVVAVG DIGKELKEKA RCTPGSFFWV
     LDPVMGDNGK LYVAEDVVPA YKSLVPYADL ILPNQFEAEL LSGVSIVDMR SLTGAIQAFH
     DKYRIPHVVI TSVRLPAAAQ PADHLSVVGS SMTSDGKARL FKIVFASIDC YFCGTGDMFG
     ALITTRMREA VEAVPGLRER ASWLSDDATP ALELPLARAT EKVLASMYEV LSRTRDAMPA
     VVERTRAAMA EGERADEKNA HYVKTKAAEL QLVQNLDCLR APATDFQAQA I
//