ID T5D8F4_HELPX Unreviewed; 375 AA.
AC T5D8F4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=2-oxoglutarate ferredoxin oxidoreductase subunit alpha {ECO:0000313|EMBL:EQL67197.1};
DE EC=1.2.7.3 {ECO:0000313|EMBL:EQL67197.1};
GN ORFNames=N408_03085 {ECO:0000313|EMBL:EQL67197.1};
OS Helicobacter pylori FD703.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1191285 {ECO:0000313|EMBL:EQL67197.1, ECO:0000313|Proteomes:UP000015969};
RN [1] {ECO:0000313|EMBL:EQL67197.1, ECO:0000313|Proteomes:UP000015969}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD703 {ECO:0000313|EMBL:EQL67197.1,
RC ECO:0000313|Proteomes:UP000015969};
RX PubMed=23012278; DOI=10.1128/JB.01278-12;
RA Gunaletchumy S.P., Teh X., Khosravi Y., Ramli N.S., Chua E.G., Kavitha T.,
RA Mason J.N., Lee H.T., Alias H., Zaidan N.Z., Yassin N.B., Tay L.C.,
RA Rudd S., Mitchell H.M., Kaakoush N.O., Loke M.F., Goh K.L., Vadivelu J.;
RT "Draft genome sequences of Helicobacter pylori isolates from Malaysia,
RT cultured from patients with functional dyspepsia and gastric cancer.";
RL J. Bacteriol. 194:5695-5696(2012).
RN [2] {ECO:0000313|EMBL:EQL67197.1, ECO:0000313|Proteomes:UP000015969}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD703 {ECO:0000313|EMBL:EQL67197.1,
RC ECO:0000313|Proteomes:UP000015969};
RX PubMed=24051312;
RA Rehvathy V., Tan M.H., Gunaletchumy S.P., Teh X., Wang S., Baybayan P.,
RA Singh S., Ashby M., Kaakoush N.O., Mitchell H.M., Croft L.J., Goh K.L.,
RA Loke M.F., Vadivelu J.;
RT "Multiple genome sequences of Helicobacter pylori strains of diverse
RT disease and antibiotic resistance backgrounds from malaysia.";
RL Genome Announc. 1:E00687-E00713(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQL67197.1}.
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DR EMBL; AKHS02000016; EQL67197.1; -; Genomic_DNA.
DR RefSeq; WP_001206816.1; NZ_AKHS02000016.1.
DR AlphaFoldDB; T5D8F4; -.
DR PATRIC; fig|1191285.4.peg.1360; -.
DR Proteomes; UP000015969; Unassembled WGS sequence.
DR GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154:SF14; 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:EQL67197.1}.
FT DOMAIN 14..243
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 275..368
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 375 AA; 41398 MW; 57BF67C1997031BA CRC64;
MREIISDGNE LVAKAAIEVG CRFFGGYPIT PSSDIMHAMS VALPKCGGHF IQMEDEISGI
SVSLGASMSG TKSMTASSGP GISLKVEQIG YSFMAEIPLV IADVMRSGPS TGMPTRVAQG
DVNFLKHPIH GDFKAVALAP ASLEEAYTET VRAFNLAEML MTPVFLLMDE TVGHMYGKVQ
IPDLEEVQKM TINRKEFLGD KKDYKPYGVA QDEPAVLNPF FKGYRYHVSG LHHGPIGFPT
EDAKIGGDLI DRLFNKIESK QDIINENEEL DLEGAEIVVI AYGSVSLAVK EALKDYNKES
KQKVGFFRPK TLWPSPAKRL KEIGDKYKKI LVIELNKGQY LEEVERAMQR KVHFLGQANG
RTISPKQIIA KLKEL
//
