ID T5DF43_HELPX Unreviewed; 159 AA.
AC T5DF43;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN ORFNames=N409_07365 {ECO:0000313|EMBL:EQL72740.1};
OS Helicobacter pylori FD719.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1191286 {ECO:0000313|EMBL:EQL72740.1, ECO:0000313|Proteomes:UP000015963};
RN [1] {ECO:0000313|EMBL:EQL72740.1, ECO:0000313|Proteomes:UP000015963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD719 {ECO:0000313|EMBL:EQL72740.1,
RC ECO:0000313|Proteomes:UP000015963};
RX PubMed=23012278; DOI=10.1128/JB.01278-12;
RA Gunaletchumy S.P., Teh X., Khosravi Y., Ramli N.S., Chua E.G., Kavitha T.,
RA Mason J.N., Lee H.T., Alias H., Zaidan N.Z., Yassin N.B., Tay L.C.,
RA Rudd S., Mitchell H.M., Kaakoush N.O., Loke M.F., Goh K.L., Vadivelu J.;
RT "Draft genome sequences of Helicobacter pylori isolates from Malaysia,
RT cultured from patients with functional dyspepsia and gastric cancer.";
RL J. Bacteriol. 194:5695-5696(2012).
RN [2] {ECO:0000313|EMBL:EQL72740.1, ECO:0000313|Proteomes:UP000015963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD719 {ECO:0000313|EMBL:EQL72740.1,
RC ECO:0000313|Proteomes:UP000015963};
RX PubMed=24051312;
RA Rehvathy V., Tan M.H., Gunaletchumy S.P., Teh X., Wang S., Baybayan P.,
RA Singh S., Ashby M., Kaakoush N.O., Mitchell H.M., Croft L.J., Goh K.L.,
RA Loke M.F., Vadivelu J.;
RT "Multiple genome sequences of Helicobacter pylori strains of diverse
RT disease and antibiotic resistance backgrounds from malaysia.";
RL Genome Announc. 1:E00687-E00713(2013).
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594, ECO:0000256|RuleBase:RU362026}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQL72740.1}.
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DR EMBL; AKHU02000051; EQL72740.1; -; Genomic_DNA.
DR AlphaFoldDB; T5DF43; -.
DR REBASE; 72583; M.HpyFD719ORF7365P.
DR PATRIC; fig|1191286.4.peg.345; -.
DR Proteomes; UP000015963; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EQL72740.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 28..153
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 159 AA; 18801 MW; 2094D340772CDCA4 CRC64;
MDFLKENLNT IIEGDCLEKL KDFPDRSVDF IFADPPYFMQ TEGELKRFEG TKFQGVEDHW
DKFDSFKQYD TFCLGWLKEC QRILKDNGSI CVIGSFHNIF RIGFHLQNLG FWILNDIIWH
KSNPVPNFAG KRLCNAHETL IWCAKKIKEK INGYHIFKN
//
