ID T5DGI1_HELPX Unreviewed; 372 AA.
AC T5DGI1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Sialidase domain-containing protein {ECO:0000259|Pfam:PF13088};
GN ORFNames=N409_05155 {ECO:0000313|EMBL:EQL73215.1};
OS Helicobacter pylori FD719.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1191286 {ECO:0000313|EMBL:EQL73215.1, ECO:0000313|Proteomes:UP000015963};
RN [1] {ECO:0000313|EMBL:EQL73215.1, ECO:0000313|Proteomes:UP000015963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD719 {ECO:0000313|EMBL:EQL73215.1,
RC ECO:0000313|Proteomes:UP000015963};
RX PubMed=23012278; DOI=10.1128/JB.01278-12;
RA Gunaletchumy S.P., Teh X., Khosravi Y., Ramli N.S., Chua E.G., Kavitha T.,
RA Mason J.N., Lee H.T., Alias H., Zaidan N.Z., Yassin N.B., Tay L.C.,
RA Rudd S., Mitchell H.M., Kaakoush N.O., Loke M.F., Goh K.L., Vadivelu J.;
RT "Draft genome sequences of Helicobacter pylori isolates from Malaysia,
RT cultured from patients with functional dyspepsia and gastric cancer.";
RL J. Bacteriol. 194:5695-5696(2012).
RN [2] {ECO:0000313|EMBL:EQL73215.1, ECO:0000313|Proteomes:UP000015963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD719 {ECO:0000313|EMBL:EQL73215.1,
RC ECO:0000313|Proteomes:UP000015963};
RX PubMed=24051312;
RA Rehvathy V., Tan M.H., Gunaletchumy S.P., Teh X., Wang S., Baybayan P.,
RA Singh S., Ashby M., Kaakoush N.O., Mitchell H.M., Croft L.J., Goh K.L.,
RA Loke M.F., Vadivelu J.;
RT "Multiple genome sequences of Helicobacter pylori strains of diverse
RT disease and antibiotic resistance backgrounds from malaysia.";
RL Genome Announc. 1:E00687-E00713(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQL73215.1}.
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DR EMBL; AKHU02000030; EQL73215.1; -; Genomic_DNA.
DR RefSeq; WP_000433761.1; NZ_AKHU02000030.1.
DR AlphaFoldDB; T5DGI1; -.
DR PATRIC; fig|1191286.4.peg.881; -.
DR Proteomes; UP000015963; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR011040; Sialidase.
DR PANTHER; PTHR43752; BNR/ASP-BOX REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR43752:SF2; BNR_ASP-BOX REPEAT FAMILY PROTEIN; 1.
DR Pfam; PF13088; BNR_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 75..344
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 372 AA; 42805 MW; 9C5D6ADA9C49187A CRC64;
MEPSRNRLKH AAFFVGLFIV LFLIIMKRQT PPYAFTPNQT LSTESPPYFT QLIVPKPNDA
LSVHASALIS LPNDNLLSAY FSGTKEGARD VKISANLFDS KINRWSEAFI LLTKEELSHY
SHEYIKKLGN PLLFLHDDKI LLFVVGVSMG GWATSKIYQL ESALEPIRFK FVRKLSLSPF
LNLSHLIKNK PLNTTDGGFM LPLYHELATQ YPLLLKFDKQ NNPKELLRPN ALNHQLQPSL
TPFKDCAIMA FRNHSFKDSL MLETCKTPTI WQKPMLTNLK NLNDALNLIN LNKELYLIHN
PSDSSLRRKE LLLSKLENPN SFKTLKILDK ADEVSYPSYS LNPHFIDIVY TYNRSHIKHI
RFNMAYLKTL LK
//
