ID T5DK72_HELPX Unreviewed; 533 AA.
AC T5DK72;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=Cell division protein FtsK {ECO:0000313|EMBL:EQL76910.1};
DE Flags: Fragment;
GN ORFNames=N410_02185 {ECO:0000313|EMBL:EQL76910.1};
OS Helicobacter pylori GC26.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1191287 {ECO:0000313|EMBL:EQL76910.1, ECO:0000313|Proteomes:UP000015972};
RN [1] {ECO:0000313|EMBL:EQL76910.1, ECO:0000313|Proteomes:UP000015972}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GC26 {ECO:0000313|EMBL:EQL76910.1,
RC ECO:0000313|Proteomes:UP000015972};
RX PubMed=23012278; DOI=10.1128/JB.01278-12;
RA Gunaletchumy S.P., Teh X., Khosravi Y., Ramli N.S., Chua E.G., Kavitha T.,
RA Mason J.N., Lee H.T., Alias H., Zaidan N.Z., Yassin N.B., Tay L.C.,
RA Rudd S., Mitchell H.M., Kaakoush N.O., Loke M.F., Goh K.L., Vadivelu J.;
RT "Draft genome sequences of Helicobacter pylori isolates from Malaysia,
RT cultured from patients with functional dyspepsia and gastric cancer.";
RL J. Bacteriol. 194:5695-5696(2012).
RN [2] {ECO:0000313|EMBL:EQL76910.1, ECO:0000313|Proteomes:UP000015972}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GC26 {ECO:0000313|EMBL:EQL76910.1,
RC ECO:0000313|Proteomes:UP000015972};
RX PubMed=24051312;
RA Rehvathy V., Tan M.H., Gunaletchumy S.P., Teh X., Wang S., Baybayan P.,
RA Singh S., Ashby M., Kaakoush N.O., Mitchell H.M., Croft L.J., Goh K.L.,
RA Loke M.F., Vadivelu J.;
RT "Multiple genome sequences of Helicobacter pylori strains of diverse
RT disease and antibiotic resistance backgrounds from malaysia.";
RL Genome Announc. 1:E00687-E00713(2013).
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQL76910.1}.
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DR EMBL; AKHV02000022; EQL76910.1; -; Genomic_DNA.
DR AlphaFoldDB; T5DK72; -.
DR PATRIC; fig|1191287.6.peg.1347; -.
DR Proteomes; UP000015972; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000313|EMBL:EQL76910.1};
KW Cell division {ECO:0000313|EMBL:EQL76910.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}.
FT DOMAIN 207..397
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 224..231
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EQL76910.1"
SQ SEQUENCE 533 AA; 59241 MW; 50DDDB33E75A3555 CRC64;
IKENIKENIK ENIKENIKEN IKEENEAQNA PSFSPITPTN AKKPVMVKEL SENKEILDGL
DYGEVQKPKD YELPTTQLLN ALCLKDTSLD ENEIDQKIQD LLSKLRTFKI DGDIIRTYSG
PIVTTFEFRP APNVKVSRIL GLSDDLAMTL CAESIRIQAP IKGKDVVGIE IPNSQSQTIY
LREILESELF QKSSSPLTLA LGKDIVGNPF ITDLKKLPHL LIAGTTGSGK SVGVNAMILS
LLYKNPPDQL KLVMIDPKMV EFSIYADIPH LLTPIITDPK KAIGALQSVA KEMERRYSLM
SEYKVKTIDS YNEQAPNNGV EAFPYLIVVI DELADLMMTG GKEAEFPIAR IAQMGRASGL
HLIVATQRPS VDVVTGLIKT NLPSRVSFRV GTKIDSKVIL DTDGAQSLLG RGDMLFTPPG
SNGLVRLHAP FATEDEIKKI VDFIKAQKEV EYDKDFLLEE SRMPLDTPNY QGDDILERAK
AVILEKKITS TSFLQRQLKI GYNQAATITD ELEAQGFLSP RNAKGNREIL QNF
//
