ID   TAPC_AERHY              Reviewed;         413 AA.
AC   P45793;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   24-JAN-2024, entry version 82.
DE   RecName: Full=Type IV pilus assembly protein TapC;
GN   Name=tapC;
OS   Aeromonas hydrophila.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=644;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Ah65;
RX   PubMed=8820654; DOI=10.1046/j.1365-2958.1996.431958.x;
RA   Pepe C.M., Eklund M.W., Strom M.S.;
RT   "Cloning of an Aeromonas hydrophila type IV pilus biogenesis gene cluster:
RT   complementation of pilus assembly functions and characterization of a type
RT   IV leader peptidase/N-methyltransferase required for extracellular protein
RT   secretion.";
RL   Mol. Microbiol. 19:857-869(1996).
CC   -!- FUNCTION: Involved in the translocation of the type IV pilin.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GSP F family. {ECO:0000305}.
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DR   EMBL; U20255; AAC43997.1; -; Genomic_DNA.
DR   PIR; S70874; S70874.
DR   AlphaFoldDB; P45793; -.
DR   SMR; P45793; -.
DR   eggNOG; COG1459; Bacteria.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR   InterPro; IPR003004; GspF/PilC.
DR   InterPro; IPR001992; T2SS_GspF/T4SS_PilC_CS.
DR   InterPro; IPR018076; T2SS_GspF_dom.
DR   InterPro; IPR042094; T2SS_GspF_sf.
DR   PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR   PANTHER; PTHR30012:SF7; PROTEIN TRANSPORT PROTEIN HOFC HOMOLOG; 1.
DR   Pfam; PF00482; T2SSF; 2.
DR   PRINTS; PR00812; BCTERIALGSPF.
DR   PROSITE; PS00874; T2SP_F; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Fimbrium biogenesis; Membrane;
KW   Protein transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..413
FT                   /note="Type IV pilus assembly protein TapC"
FT                   /id="PRO_0000207843"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   413 AA;  45386 MW;  A5EA2CF03EF90F86 CRC64;
     MATLTQKQNA PKKVFAFRWS GVNRKGQKVS GELQADSINT VKAELRKQGV NVTKVSKKSQ
     GLFSKGGAKI KPMDIAIVSR QITTMLSAGV PLVQSLQIIA RSHEKASMRE LMGQIAADVE
     TGTPMSEALR RHPRHFDALY CDLVEAGEQS GALETIYDRI ATYREKSEAL KSKIKKAMFY
     PAMVILVAIV VTSILLLFVI PQFEDIFKSF GAELPIFTQF VIGISRFMQH WWYVIFGGTA
     FAIFLYVRAW RASQKVKDNT DKFILTIPVV GMILHKAAMA RFARTLSTTF SAGIPLVDAL
     ISAAGASGNY VYRTAVMAIR NEVVAGMQIN VAMRTVDLFP DMVIQMVMIG EESGAIDDML
     SKVATIFEQE VDDLVDGLTS LLEPLIMVVL GVLVGGMVVA MYLPIFKLGD LVG
//