ID TM41_CAEEL Reviewed; 246 AA.
AC O62126;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE RecName: Full=Transmembrane protein 41 homolog;
GN Name=tag-175; ORFNames=D2013.10;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM41 family. {ECO:0000305}.
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DR EMBL; Z47808; CAA87776.1; -; Genomic_DNA.
DR PIR; T20341; T20341.
DR RefSeq; NP_495985.1; NM_063584.1.
DR AlphaFoldDB; O62126; -.
DR BioGRID; 48748; 2.
DR DIP; DIP-25887N; -.
DR STRING; 6239.D2013.10.1; -.
DR PaxDb; 6239-D2013-10; -.
DR EnsemblMetazoa; D2013.10.1; D2013.10.1; WBGene00006520.
DR GeneID; 183942; -.
DR KEGG; cel:CELE_D2013.10; -.
DR UCSC; D2013.10; c. elegans.
DR AGR; WB:WBGene00006520; -.
DR WormBase; D2013.10; CE17622; WBGene00006520; tag-175.
DR eggNOG; KOG3140; Eukaryota.
DR GeneTree; ENSGT00940000156956; -.
DR HOGENOM; CLU_038944_0_1_1; -.
DR InParanoid; O62126; -.
DR OMA; CIKIPRD; -.
DR OrthoDB; 178922at2759; -.
DR PhylomeDB; O62126; -.
DR PRO; PR:O62126; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00006520; Expressed in pharyngeal muscle cell (C elegans) and 4 other cell types or tissues.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR InterPro; IPR045014; TM41A/B.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR43220; -; 1.
DR PANTHER; PTHR43220:SF18; TRANSMEMBRANE PROTEIN 41B; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..246
FT /note="Transmembrane protein 41 homolog"
FT /id="PRO_0000291945"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 246 AA; 27502 MW; 77DAD46573A5380E CRC64;
METKSSQTSH PWLVLLIFAT FAVSIFAVYS NFPEVSADEK VHLKYPRNLE DAKQLGRVLS
KYKENNYSVV LCGVIVVYVF LQSFAIPGSI FLTILSGYLF PFYVAIVLVC SCSATGAAIC
YTISKLFGRS FVLQKFPERI AKWQDDLSKH RDDFLNYMIF LRVTPIVPNW LINIASPVLD
VPLAPFFWGT FLGVAPPSFL YIQAGSTLEQ LSHTSVAWSW SSIVLLTGSA ILSLAPILLK
KKLKSD
//
