ID TPC2L_PONAB Reviewed; 109 AA.
AC Q5RBK9;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE RecName: Full=Trafficking protein particle complex subunit 2-like protein;
GN Name=TRAPPC2L;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in vesicular transport from endoplasmic
CC reticulum to Golgi. {ECO:0000250}.
CC -!- SUBUNIT: Component of the multisubunit TRAPP (transport protein
CC particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3,
CC TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and
CC TRAPPC12. Interacts with the heterodimer TRAPPC3-TRAPPC6A (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250}.
CC Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TRAPP small subunits family. Sedlin
CC subfamily. {ECO:0000305}.
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DR EMBL; CR858631; CAH90851.1; -; mRNA.
DR RefSeq; NP_001125486.1; NM_001132014.1.
DR AlphaFoldDB; Q5RBK9; -.
DR SMR; Q5RBK9; -.
DR STRING; 9601.ENSPPYP00000008629; -.
DR GeneID; 100172395; -.
DR KEGG; pon:100172395; -.
DR CTD; 51693; -.
DR InParanoid; Q5RBK9; -.
DR OrthoDB; 2724142at2759; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14854; TRAPPC2L; 1.
DR Gene3D; 3.30.450.70; -; 2.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR006722; Sedlin.
DR InterPro; IPR044760; TRAPPC2L.
DR PANTHER; PTHR12403; TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR12403:SF11; TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN; 1.
DR Pfam; PF04628; Sedlin_N; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus;
KW Reference proteome; Transport.
FT CHAIN 1..109
FT /note="Trafficking protein particle complex subunit 2-like
FT protein"
FT /id="PRO_0000294453"
SQ SEQUENCE 109 AA; 12683 MW; 3E7B9A5032076611 CRC64;
MAVCIAVIAK ENYPLYIRST PTENKLKFHY MVHTSLDVVD EKISAMGKAL VDQRELYLGL
LYPTEDYKMF RKLHNSYTDV MCNPFYNPGD RIQSRAFDNM VTSMMIQVC
//
