ID TRUB_CORGB Reviewed; 297 AA.
AC A4QEY6;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 01-MAY-2013, entry version 44.
DE RecName: Full=tRNA pseudouridine synthase B;
DE EC=5.4.99.25;
DE AltName: Full=tRNA pseudouridine(55) synthase;
DE Short=Psi55 synthase;
DE AltName: Full=tRNA pseudouridylate synthase;
DE AltName: Full=tRNA-uridine isomerase;
GN Name=truB; OrderedLocusNames=cgR_1808;
OS Corynebacterium glutamicum (strain R).
OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=340322;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R;
RX PubMed=17379713; DOI=10.1099/mic.0.2006/003657-0;
RA Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N.,
RA Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.;
RT "Comparative analysis of the Corynebacterium glutamicum group and
RT complete genome sequence of strain R.";
RL Microbiology 153:1042-1058(2007).
CC -!- FUNCTION: Responsible for synthesis of pseudouridine from uracil-
CC 55 in the psi GC loop of transfer RNAs (By similarity).
CC -!- CATALYTIC ACTIVITY: tRNA uridine(55) = tRNA pseudouridine(55).
CC -!- SIMILARITY: Belongs to the pseudouridine synthase TruB family.
CC Type 1 subfamily.
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DR EMBL; AP009044; BAF54802.1; -; Genomic_DNA.
DR RefSeq; YP_001138704.1; NC_009342.1.
DR ProteinModelPortal; A4QEY6; -.
DR STRING; 340322.cgR_1808; -.
DR EnsemblBacteria; BAF54802; BAF54802; cgR_1808.
DR GeneID; 4994252; -.
DR KEGG; cgt:cgR_1808; -.
DR PATRIC; 21508228; VBICorGlu58097_1861.
DR eggNOG; COG0130; -.
DR HOGENOM; HOG000231225; -.
DR KO; K03177; -.
DR OMA; YRFHIAW; -.
DR ProtClustDB; PRK03287; -.
DR BioCyc; CGLU340322:GJBE-1888-MONOMER; -.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:HAMAP.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0031119; P:tRNA pseudouridine synthesis; IEA:HAMAP.
DR HAMAP; MF_01080; TruB_bact; 1; -.
DR InterPro; IPR002501; PsdUridine_synth.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR InterPro; IPR015947; PUA-like_domain.
DR InterPro; IPR015225; tRNA_psdUridine_synth_fam2_C.
DR InterPro; IPR014780; tRNA_psdUridine_synth_TruB.
DR PANTHER; PTHR13767; PTHR13767; 1.
DR Pfam; PF09142; TruB_C; 1.
DR Pfam; PF01509; TruB_N; 1.
DR SUPFAM; SSF55120; PsdUridine_synth_cat_dom; 1.
DR SUPFAM; SSF88697; PUA-like; 1.
DR TIGRFAMs; TIGR00431; TruB; 1.
PE 3: Inferred from homology;
KW Complete proteome; Isomerase; tRNA processing.
FT CHAIN 1 297 tRNA pseudouridine synthase B.
FT /FTId=PRO_1000084577.
FT ACT_SITE 44 44 Nucleophile (By similarity).
SQ SEQUENCE 297 AA; 31846 MW; 7909C21F4FAF6B12 CRC64;
MNAPAPKPGL VIVDKPAGMT SHDVVSKLRR AFSTRKVGHA GTLDPMATGV LVVGIERGTR
FLAHMVASTK AYDATIRLGA ATSTDDAEGE VISTTDASGL DHRAILAEIA NLTGDIMQKP
TKVSAIKIDG KRAHERVRDG EEVDIPARPV TVSVFDVLDY RVDSEFYDLD VRVHCSSGTY
IRALARDLGN ALQVGGHLTA LRRTEVGPFT LNDATPLSKL QENPELSLNL DQALTRSYPV
LDITEDEGVD LSMGKWLEPR GLKGVHAAVT PSGKAVALIE EKGKRLATVF VAHPNTL
//
