ID TTC32_HUMAN Reviewed; 151 AA.
AC Q5I0X7;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 24-JAN-2024, entry version 140.
DE RecName: Full=Tetratricopeptide repeat protein 32;
DE Short=TPR repeat protein 32;
GN Name=TTC32;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q5I0X7; Q99856: ARID3A; NbExp=3; IntAct=EBI-8636434, EBI-5458244;
CC Q5I0X7; Q8TES7-6: FBF1; NbExp=3; IntAct=EBI-8636434, EBI-10244131;
CC Q5I0X7; Q9Y5V3: MAGED1; NbExp=3; IntAct=EBI-8636434, EBI-716006;
CC Q5I0X7; Q9GZV8: PRDM14; NbExp=3; IntAct=EBI-8636434, EBI-3957793;
CC Q5I0X7; Q9HCM9: TRIM39; NbExp=3; IntAct=EBI-8636434, EBI-739510;
CC Q5I0X7; Q99757: TXN2; NbExp=3; IntAct=EBI-8636434, EBI-2932492;
CC Q5I0X7; P17022: ZNF18; NbExp=3; IntAct=EBI-8636434, EBI-8648067;
CC Q5I0X7; Q9P2Y4: ZNF219; NbExp=3; IntAct=EBI-8636434, EBI-3937106;
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DR EMBL; BC057850; AAH57850.1; -; mRNA.
DR CCDS; CCDS33151.1; -.
DR RefSeq; NP_001008238.1; NM_001008237.2.
DR AlphaFoldDB; Q5I0X7; -.
DR SMR; Q5I0X7; -.
DR BioGRID; 126236; 12.
DR IntAct; Q5I0X7; 10.
DR MINT; Q5I0X7; -.
DR STRING; 9606.ENSP00000333018; -.
DR iPTMnet; Q5I0X7; -.
DR PhosphoSitePlus; Q5I0X7; -.
DR BioMuta; TTC32; -.
DR DMDM; 74755518; -.
DR jPOST; Q5I0X7; -.
DR MassIVE; Q5I0X7; -.
DR MaxQB; Q5I0X7; -.
DR PaxDb; 9606-ENSP00000333018; -.
DR PeptideAtlas; Q5I0X7; -.
DR ProteomicsDB; 62970; -.
DR Pumba; Q5I0X7; -.
DR Antibodypedia; 27107; 275 antibodies from 20 providers.
DR DNASU; 130502; -.
DR Ensembl; ENST00000333610.4; ENSP00000333018.3; ENSG00000183891.6.
DR GeneID; 130502; -.
DR KEGG; hsa:130502; -.
DR MANE-Select; ENST00000333610.4; ENSP00000333018.3; NM_001008237.3; NP_001008238.1.
DR UCSC; uc002rdg.4; human.
DR AGR; HGNC:32954; -.
DR CTD; 130502; -.
DR GeneCards; TTC32; -.
DR HGNC; HGNC:32954; TTC32.
DR HPA; ENSG00000183891; Low tissue specificity.
DR neXtProt; NX_Q5I0X7; -.
DR OpenTargets; ENSG00000183891; -.
DR PharmGKB; PA145147867; -.
DR VEuPathDB; HostDB:ENSG00000183891; -.
DR eggNOG; KOG1124; Eukaryota.
DR GeneTree; ENSGT00390000011905; -.
DR HOGENOM; CLU_151642_0_0_1; -.
DR InParanoid; Q5I0X7; -.
DR OMA; FEIPYYN; -.
DR OrthoDB; 3082982at2759; -.
DR PhylomeDB; Q5I0X7; -.
DR PathwayCommons; Q5I0X7; -.
DR SignaLink; Q5I0X7; -.
DR BioGRID-ORCS; 130502; 13 hits in 1155 CRISPR screens.
DR GenomeRNAi; 130502; -.
DR Pharos; Q5I0X7; Tdark.
DR PRO; PR:Q5I0X7; -.
DR Proteomes; UP000005640; Chromosome 2.
DR RNAct; Q5I0X7; Protein.
DR Bgee; ENSG00000183891; Expressed in corpus epididymis and 180 other cell types or tissues.
DR ExpressionAtlas; Q5I0X7; baseline and differential.
DR Genevisible; Q5I0X7; HS.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR47059; TETRATRICOPEPTIDE REPEAT PROTEIN 32; 1.
DR PANTHER; PTHR47059:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 32; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..151
FT /note="Tetratricopeptide repeat protein 32"
FT /id="PRO_0000263100"
FT REPEAT 8..41
FT /note="TPR 1"
FT REPEAT 58..91
FT /note="TPR 2"
FT REPEAT 92..125
FT /note="TPR 3"
SQ SEQUENCE 151 AA; 17296 MW; 81BE35CDA095B2D9 CRC64;
MEGQRQESHA TLTLAQAHFN NGEYAEAEAL YSAYIRRCAC AASSDESPGS KCSPEDLATA
YNNRGQIKYF RVDFYEAMDD YTSAIEVQPN FEVPYYNRGL ILYRLGYFDD ALEDFKKVLD
LNPGFQDATL SLKQTILDKE EKQRRNVAKN Y
//
