ID U1FBD5_TRESO Unreviewed; 692 AA.
AC U1FBD5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Oxaloacetate decarboxylase alpha subunit {ECO:0000313|EMBL:ERF61477.1};
DE EC=4.1.1.3 {ECO:0000313|EMBL:ERF61477.1};
GN Name=oadA {ECO:0000313|EMBL:ERF61477.1};
GN ORFNames=HMPREF1325_0761 {ECO:0000313|EMBL:ERF61477.1};
OS Treponema socranskii subsp. socranskii VPI DR56BR1116 = ATCC 35536.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=1125725 {ECO:0000313|EMBL:ERF61477.1, ECO:0000313|Proteomes:UP000016412};
RN [1] {ECO:0000313|EMBL:ERF61477.1, ECO:0000313|Proteomes:UP000016412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VPI DR56BR1116 {ECO:0000313|EMBL:ERF61477.1,
RC ECO:0000313|Proteomes:UP000016412};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERF61477.1}.
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DR EMBL; AUZJ01000012; ERF61477.1; -; Genomic_DNA.
DR RefSeq; WP_021329596.1; NZ_AUZJ01000012.1.
DR AlphaFoldDB; U1FBD5; -.
DR STRING; 1125725.HMPREF1325_0761; -.
DR PATRIC; fig|1125725.3.peg.514; -.
DR eggNOG; COG0511; Bacteria.
DR eggNOG; COG5016; Bacteria.
DR OrthoDB; 9807469at2; -.
DR Proteomes; UP000016412; Unassembled WGS sequence.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 2.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR005776; OadA.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR01108; oadA; 1.
DR PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR Pfam; PF00364; Biotin_lipoyl; 2.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 2.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 2.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:ERF61477.1}.
FT DOMAIN 5..265
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT DOMAIN 514..593
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT DOMAIN 616..692
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 692 AA; 73609 MW; 1DD488D7D22E7453 CRC64;
MAKKVHITEL VLRDAHQSLL ATRMTTADML PACPMIDKIG YYSAEAWGGA TYDSCIRFLN
EDPWERLRKL HAAMPNTKIM MLLRGQNLLG YRHYADDVVD KFVEAAAKNG IGIFRIFDAC
NDPRNLERSA KAAKKTGKHV QMAISYATTP YHTKEVYADL AKRYAEFGAD SICIKDMSGL
LKPFEAYDLV KAIKAKVDMP IEIHSHSTTG LSVATLLKAS EAGADVLDTA ISSMAMGTSH
SPTETVVEML KGSEYDTGLD TKALLEIAAY FRDVREHYAS LESKFHGADT RILVSQVPGG
MLSNLEKQLK EQCAADKIDD VLKEIPIVQK DVGYVPLVTP TSQIVGTQAV FNVLFGRYAR
LTQEFRDLLT GRYGATPAAV NADLQKEALK QNNMDSVVTC RPADLISNEW DKCVEDAKKA
GGDGSDEDVL TYAMFPKVAE KFFKERSKGP VDAQKTFGVK PVSESASASA PKSGSYTVSV
NGTPYSVTTS AGSDTIIVNG TSYNVSFGDA APSSAPVSAP VVTGGADIKA PVAGTLLRYV
AQNGAEVKKG DTVLMIESMK MELEVKAPAD GKINFIAQPG AQIAAGEVIA SLGGTVAAAP
APKPAAAAPV PKAAPVPSAA STGGKPVKAP VAGTLLRYEV GEGDQVKADT TVIMIESMKM
ELEIKAGAAG AVHFLVQPGS QITAGQALAE IK
//
