ID U1G9F4_ENDPU Unreviewed; 1789 AA.
AC U1G9F4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EPUS_02782 {ECO:0000313|EMBL:ERF68326.1};
OS Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Verrucariales; Verrucariaceae; Endocarpon.
OX NCBI_TaxID=1263415 {ECO:0000313|EMBL:ERF68326.1, ECO:0000313|Proteomes:UP000019373};
RN [1] {ECO:0000313|Proteomes:UP000019373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z07020 / HMAS-L-300199 {ECO:0000313|Proteomes:UP000019373};
RX PubMed=24438332; DOI=10.1186/1471-2164-15-34;
RA Wang Y.-Y., Liu B., Zhang X.-Y., Zhou Q.-M., Zhang T., Li H., Yu Y.-F.,
RA Zhang X.-L., Hao X.-Y., Wang M., Wang L., Wei J.-C.;
RT "Genome characteristics reveal the impact of lichenization on lichen-
RT forming fungus Endocarpon pusillum Hedwig (Verrucariales, Ascomycota).";
RL BMC Genomics 15:34-34(2014).
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DR EMBL; KE721523; ERF68326.1; -; Genomic_DNA.
DR RefSeq; XP_007806101.1; XM_007807910.1.
DR GeneID; 19237832; -.
DR eggNOG; KOG0927; Eukaryota.
DR eggNOG; KOG2114; Eukaryota.
DR HOGENOM; CLU_238384_0_0_1; -.
DR OrthoDB; 5491867at2759; -.
DR Proteomes; UP000019373; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProt.
DR GO; GO:0099023; C:vesicle tethering complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd16688; RING-H2_Vps11; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR024763; VPS11_C.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23323:SF24; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF00637; Clathrin; 1.
DR Pfam; PF12451; VPS11_C; 1.
DR Pfam; PF17122; zf-C3H2C3; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS50236; CHCR; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019373};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 36..304
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 449..771
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1679..1729
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 404..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1393..1427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1395..1416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1789 AA; 198046 MW; 01462B0AC02FCD20 CRC64;
MKVPITLPIR YRAPPSIENL IQIQNGTFYR QHPGGLQESN TPLFPNLYFS LPAFPLRRDS
ETGKQQQHWA VVGASGGSTF LEILRGTHIC LPPNARTFPY LSSEDIEAKD YRLRSPTWAI
QYVGFTSGKG QGLVGGIRGS YLSARYESRR EETDWSVLQY LKGEMELNPS KELHYEDASF
NALLSQVIKD LRLEQLTSLP VSNLSNGQTR RARIAKALLG RPEVLLLDEP FMGLDPPTLV
SLSPILRGLA YKSSPRLIMS LRPQDPIPDW ITHLAVLGHQ DTLALAGPKK EVLFAVHRWA
NAHKGPQNGT AAKMAALMTN RHGPPPLDFG YTLSATGVSR DVTNSQIVSS KTPTYISATD
ELVPEHLSVA YRLVWQKAAG KPREKADLDD LLSLTCLLPA EFNRQDDVPA PSNESFSISE
DPRRGQHNSG FPVSNFPMRP HPELGKSLIE LKNVIVSYGS KTVLGYGVQS GFQVPGLNLD
IRQGTRLALL GPNGSGKTTL LSLLTSDHPQ SYSLPIKYFG RSRLPSPGQP GVSLWEIQSR
IGHSSPEIHA FFPKGLTIRR SLESAWAETF AAKPEPTNSS KALVDAFLRW WEPELNPCHQ
PLPPLEAPAI PIDDSVSSSY PSFKHSSQTA NELEWASLPL NTFGSLSFQS QRLLLLLRAI
IKTPDIVILD EAFSGFSPEV RDKAMRFLGA GENSVPHQHQ AATYRTCMDD GDGESSRWPL
RDDRTRVETI CHTTRVTPNE PIVGKEGMTH EKKKRVDRLR RKTKSELTAE GDLADDSVEY
AFHGLSNEQA LIVVSHVREE IPDLVNEYIR LPGEEEVSEQ RRGIEMVVAT GVLACKSEVI
ALPTIAGSDS IFLGDSNGDV RILSRALRVV RLFHAADPSS HGSITHLKQI DATSLLVTIC
EDLSSDPVLK VWALDKEEKK TKGPKCLCTI GVQNGRRQFP VSAFVALEDL TQVAVGFANG
AVTVIRGDLI HDRGTKQRIV FESEEPITGL AIRESPMTIL YIATTGRISN LVISGKGQGQ
PPRTVDSQGC AVRCMSVDKE TGDIIIARDD AVYYYGPNGR GPSFAFDGPK KMITTFKDYV
GLVCPPKVAQ VSKSNTYRRL GGSGMGDLFS TSSFSLLETD LRYIAHTESL STELYRYEEK
TLQQKLEILY QRNLYILAIN LAQKAGVDTA TQNVIFRKYG DYLYQKGDYD TAMQQYLRAI
DNTEPSQILR KFLDTQRIHN LIEYLEELHE HDKATADHTT LLLNCYAKLK DTEKLDAFIR
APGELKFDLE TAISMCRQGG YFEQAAYLAT KHGENSLVVD ILIEDSKKYP EALAYIWQLE
PLAAYPNLMK YSRVLLEHCP DEATQVFIDY YTGNYRPKEE VTATQEPQPQ NQASAFQNLS
ALLPLPYMNR SAVASPAPEA QQQTTTADTK LASNADTPTP EYPIPRPRTA FSSFIPHPSH
FIRFLEALTS QPNISSTDKT DLYTTLFEMY LEAANSESTT SSEREAWQHK AKALITSQPQ
ISTQSSDQPL SFIPTSSVLL LSSLSNFPTG TTLVRERANL YTDILRSHTT AKDTSGAISA
LRRYGPEDPS LYPIALSYFS SSTTILSQPG VKEELQSVLR KIDQDSLMAP LQVVKVLSQG
GAVSMGMVKS YLSDNISRER KEIRNNRTLI ESYRKESAAK ISELEDLGSK PIVFQARRCS
ACGGQLDLPT VHFACKHSFH QRCLNTGSVS QAAQADATAE GRAECPVCKP QNDTIKAHRR
AQVESADQHE LFKAALERSQ ERFETVAEFF GRGVMNLNSV GNGPGAGGG
//
