ID U1GRP3_ENDPU Unreviewed; 666 AA.
AC U1GRP3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=CPL domain-containing protein {ECO:0000259|Pfam:PF08144};
GN ORFNames=EPUS_00771 {ECO:0000313|EMBL:ERF74641.1};
OS Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Verrucariales; Verrucariaceae; Endocarpon.
OX NCBI_TaxID=1263415 {ECO:0000313|EMBL:ERF74641.1, ECO:0000313|Proteomes:UP000019373};
RN [1] {ECO:0000313|Proteomes:UP000019373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z07020 / HMAS-L-300199 {ECO:0000313|Proteomes:UP000019373};
RX PubMed=24438332; DOI=10.1186/1471-2164-15-34;
RA Wang Y.-Y., Liu B., Zhang X.-Y., Zhou Q.-M., Zhang T., Li H., Yu Y.-F.,
RA Zhang X.-L., Hao X.-Y., Wang M., Wang L., Wei J.-C.;
RT "Genome characteristics reveal the impact of lichenization on lichen-
RT forming fungus Endocarpon pusillum Hedwig (Verrucariales, Ascomycota).";
RL BMC Genomics 15:34-34(2014).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit. {ECO:0000256|ARBA:ARBA00024893}.
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DR EMBL; KE720872; ERF74641.1; -; Genomic_DNA.
DR RefSeq; XP_007799742.1; XM_007801551.1.
DR AlphaFoldDB; U1GRP3; -.
DR GeneID; 19235832; -.
DR eggNOG; KOG2050; Eukaryota.
DR HOGENOM; CLU_013994_1_0_1; -.
DR OMA; YGPEFSI; -.
DR OrthoDB; 5479527at2759; -.
DR Proteomes; UP000019373; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012959; CPL_dom.
DR InterPro; IPR040059; PUM3.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13389:SF0; PUMILIO HOMOLOG 3; 1.
DR PANTHER; PTHR13389; UNCHARACTERIZED; 1.
DR Pfam; PF08144; CPL; 1.
DR SMART; SM00025; Pumilio; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019373};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 449..576
FT /note="CPL"
FT /evidence="ECO:0000259|Pfam:PF08144"
FT REGION 1..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 74994 MW; E10D06F106C85464 CRC64;
MAGIKRYRDE SRSTSVKKAK VDVSVQQQKL IKTTVRQSVL PSPEDSSAAS EDLVNTHSPK
IPPRQALKDG APAPKRKISQ TNRPANLSTS TQGGQVVNGS SSREAHAKQK VLAQERKAVK
PNADSIARSK KIWERLRRKS HVPKDERDKL VIELFSIITG RVKDFVFKHD SVRVIQTAVK
YGNLQQRRQI AQELKGEYRS LAESRYAKFL IAKLVVGDDE VRDIIVPEFY GHVRRLIRHP
EAAWIMDDIY RTIATPEQKA RLLREWYGHE FVIFQSSADS ALRGDLHQIL MENPEKRGPI
MQHLKEMTNH LLQKKTTGFT MLHDALLQYF INCTSGGSEA TEVIELLKDD EEGDCLKNMA
FTKSGSRLVC LALAYSNSKD RRTILKVFKG VMKMLAGDAH GHVILLTAFD VIDDTVMTAK
AVFPELLCKD SEEQQRQTEL VLQVEHLTAR IPFLYLLSPD LPKWLLPNQD TSILKEIHEI
RKTTSKKDPQ IRRQELVKAL SQPLIDLIGQ QTELLVSSSF GCQFINEVMF GGVGDKHAAL
ESLAVIARDK PELMNTPYAG RMLKSLVQGG PFDKESKEVR VTDPPLRFES MLYSKCRDGI
VNWASGANSF IVVAMLESPD MRDRESLVDA LRDQVQVLRE AAKGSGSDKK GNAGTKILLQ
QMEKSR
//
