ID U1HS23_ENDPU Unreviewed; 632 AA.
AC U1HS23;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Mitochondrial import receptor subunit tom-70 {ECO:0000313|EMBL:ERF73325.1};
GN ORFNames=EPUS_03158 {ECO:0000313|EMBL:ERF73325.1};
OS Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Verrucariales; Verrucariaceae; Endocarpon.
OX NCBI_TaxID=1263415 {ECO:0000313|EMBL:ERF73325.1, ECO:0000313|Proteomes:UP000019373};
RN [1] {ECO:0000313|Proteomes:UP000019373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z07020 / HMAS-L-300199 {ECO:0000313|Proteomes:UP000019373};
RX PubMed=24438332; DOI=10.1186/1471-2164-15-34;
RA Wang Y.-Y., Liu B., Zhang X.-Y., Zhou Q.-M., Zhang T., Li H., Yu Y.-F.,
RA Zhang X.-L., Hao X.-Y., Wang M., Wang L., Wei J.-C.;
RT "Genome characteristics reveal the impact of lichenization on lichen-
RT forming fungus Endocarpon pusillum Hedwig (Verrucariales, Ascomycota).";
RL BMC Genomics 15:34-34(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004572}.
CC -!- SIMILARITY: Belongs to the Tom70 family.
CC {ECO:0000256|ARBA:ARBA00038030}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE720961; ERF73325.1; -; Genomic_DNA.
DR RefSeq; XP_007801098.1; XM_007802907.1.
DR AlphaFoldDB; U1HS23; -.
DR GeneID; 19238205; -.
DR eggNOG; KOG0547; Eukaryota.
DR HOGENOM; CLU_017516_0_1_1; -.
DR OMA; QWRGDIE; -.
DR OrthoDB; 1083789at2759; -.
DR Proteomes; UP000019373; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR005687; Tom70.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR NCBIfam; TIGR00990; 3a0801s09; 1.
DR PANTHER; PTHR46208; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70; 1.
DR PANTHER; PTHR46208:SF1; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70; 1.
DR Pfam; PF13432; TPR_16; 2.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Receptor {ECO:0000313|EMBL:ERF73325.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019373};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 413..446
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 481..514
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 556..589
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 69..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 632 AA; 70120 MW; 6D9CF4FB9BE32D89 CRC64;
MSTVPIPVQL APPSGSPPSS SSSLWDRVST WATENKAIVY TIAGTVVVIT GAGIVYYLSD
SRKNIKGASI SDEKRKSKKE RRKEKKAAED GKSASPSIKD EEAGTAMPAP KAASVEAEDD
LPQIDETTVD SFSQEDRKSY AAKLKAAGNK AYGSKDYNKA IELYGKAILC KPDPVYYSNR
AACYNVLSDW DKVVEDTSAA IAMDAEYVKA LNRRAHAYEH LGMYSEALLD YTASCIIDGF
KNEQSAQSVE RLLKKVAEKK GKAILEAKGR KLPSPTFVTN YLQSFRPQPP PAGLEESVQL
DENTGLGQLQ RGLIALDKKT GEGYEEAAKS FEKAIELNDL GQHEAFGLNM RATFRYLEGD
TTQALEDLTK SVTLKPSLTQ SLIKRASMHL EMSNREAAAD DFEQATAQNK DDPDIFYHRA
QLHFILGEFP EAAKDYQKSI DLDPAFIFSH IQLGVTQYKM GSVASSMATF RRTIKKFDKT
PDVYNYYGEL LLDQQKYQEA IEKFETAVDM EKQSKPMSMN VLPLINKALA LFQWKQDFQE
AESLCQKALI IDPECDIAVA TMAQLLLQQG KVTDALKYFE RAAELSRTEG EIVNALSYAE
ATRTQLEVSE KYPQLSQRLQ QMGTAGPGMP MR
//
