ID U1HSZ5_ENDPU Unreviewed; 941 AA.
AC U1HSZ5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Small COPII coat GTPase sar1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=EPUS_00918 {ECO:0000313|EMBL:ERF73665.1};
OS Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Verrucariales; Verrucariaceae; Endocarpon.
OX NCBI_TaxID=1263415 {ECO:0000313|EMBL:ERF73665.1, ECO:0000313|Proteomes:UP000019373};
RN [1] {ECO:0000313|Proteomes:UP000019373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z07020 / HMAS-L-300199 {ECO:0000313|Proteomes:UP000019373};
RX PubMed=24438332; DOI=10.1186/1471-2164-15-34;
RA Wang Y.-Y., Liu B., Zhang X.-Y., Zhou Q.-M., Zhang T., Li H., Yu Y.-F.,
RA Zhang X.-L., Hao X.-Y., Wang M., Wang L., Wei J.-C.;
RT "Genome characteristics reveal the impact of lichenization on lichen-
RT forming fungus Endocarpon pusillum Hedwig (Verrucariales, Ascomycota).";
RL BMC Genomics 15:34-34(2014).
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. SAR1 family.
CC {ECO:0000256|ARBA:ARBA00007507}.
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DR EMBL; KE720941; ERF73665.1; -; Genomic_DNA.
DR RefSeq; XP_007800668.1; XM_007802477.1.
DR AlphaFoldDB; U1HSZ5; -.
DR GeneID; 19235978; -.
DR eggNOG; KOG0077; Eukaryota.
DR HOGENOM; CLU_014084_0_0_1; -.
DR OMA; ITLNDCM; -.
DR OrthoDB; 2731604at2759; -.
DR Proteomes; UP000019373; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd00879; Sar1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR018853; DUF2457.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR006687; Small_GTPase_SAR1.
DR PANTHER; PTHR45684; RE74312P; 1.
DR PANTHER; PTHR45684:SF2; RE74312P; 1.
DR Pfam; PF00025; Arf; 2.
DR Pfam; PF10446; DUF2457; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51422; SAR1; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019373}.
FT REGION 1..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 331..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..368
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..447
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..527
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..551
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..571
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 941 AA; 104852 MW; 14E07C102451C493 CRC64;
MFHLSNTSNP LSSEEEITGD VDEPPDEPLS PLQMNPTMVQ QPQQPSTYTR SALPAMDRKE
SLLTRALMTG SNGDISSSPT SPISGAASRA STFSNASVPS TAELTSDADD TSPTRSATPS
PPLPVALYHE IHATNKTPLP PTRISFATGK QQEKLVADAS AESQIEAKMG RKRCITFACA
SKPAVKEPHA AKEERMEIAQ PPKRKCLLTF ACPARPAQKQ DPGPEAAEAR RDSGSSSAND
ITAPSNEPHG GERQEHAQPC KVPLITVDTR KNALKSPTSP KQSDVKSSDA SPFHEFATSN
DHDDAWVREP IDTQRKLTLL DCMKKENAIR KIGEEAEEEA EQEEKEEDEF DDDNEDGINE
DDFAPSDDGN ESDNEKGFAE SDDDSDGESE DQFWIPSNNT TAATSVDHSS PHRPFGRRRQ
RGSSMDSLSD HGSRQEKRSE SVDIKHPKHR RTSKGHQMRP GTPELPDSTD FVCGTLDEDR
PLEAAYISCR EQRKREKHIL IPQDIDPSFP TTDPEDMDED DDEDLDTPED HLWLKNQLEG
SEDDSTRGHA SKHHKMCSKL RSPRRAHSPP PKHGVHCSPP PPRQTVRRSS PAPNSRLFGH
SPQRLHSPPP AMKWRSPPGT RRSSPTGMAL MPHQTEGLVI SRLGQRPHMT RTASLPRTPN
PFFHNYHART HQNDRVVYGG MTPGREMHVR GPVDIVIGLE KKRQKRKEKF WRQHCRKAAK
EQAERKTLRG RGAERMLYDV LASLGLLNKH AKLLFLGLDN AGKTTLLHML KNDRVAILQP
TLHPTSEELA IGNNRFTTFD LGGHQQGQCT PFFNITYVYQ QGFGGIAGAR RLWRDYFPEV
SGIVFLVDAK DHERLPESKL ELDALLAMED LAKVPFLILG NKIDHPDAVS EDELRHQLGL
YQTTGKGKVP LEGIRPIEVF MCSVVMRQGY GEGIRWMSQY V
//
