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Database: UniProt
Entry: U1LVL0_ASCSU
LinkDB: U1LVL0_ASCSU
Original site: U1LVL0_ASCSU 
ID   U1LVL0_ASCSU            Unreviewed;      1792 AA.
AC   U1LVL0;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   07-JUN-2017, entry version 22.
DE   SubName: Full=Sodium leak channel non-selective protein {ECO:0000313|EMBL:ERG81059.1};
GN   ORFNames=ASU_10808 {ECO:0000313|EMBL:ERG81059.1};
OS   Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Ascaridida;
OC   Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6253 {ECO:0000313|EMBL:ERG81059.1, ECO:0000313|Proteomes:UP000017900};
RN   [1] {ECO:0000313|EMBL:ERG81059.1, ECO:0000313|Proteomes:UP000017900}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Sperm {ECO:0000313|EMBL:ERG81059.1};
RX   PubMed=21685128; DOI=10.1101/gr.121426.111;
RA   Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA   Davis R.E.;
RT   "Deep small RNA sequencing from the nematode Ascaris reveals
RT   conservation, functional diversification, and novel developmental
RT   profiles.";
RL   Genome Res. 21:1462-1477(2011).
RN   [2] {ECO:0000313|EMBL:ERG81059.1, ECO:0000313|Proteomes:UP000017900}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Sperm {ECO:0000313|EMBL:ERG81059.1};
RX   PubMed=23123092; DOI=10.1016/j.devcel.2012.09.020;
RA   Wang J., Mitreva M., Berriman M., Thorne A., Magrini V.,
RA   Koutsovoulos G., Kumar S., Blaxter M.L., Davis R.E.;
RT   "Silencing of germline-expressed genes by DNA elimination in somatic
RT   cells.";
RL   Dev. Cell 23:1072-1080(2012).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ERG81059.1}.
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DR   EMBL; AEUI02000509; ERG81059.1; -; Genomic_DNA.
DR   Proteomes; UP000017900; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000017900};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017900};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     97       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    103    124       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    145    163       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    175    200       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    220    242       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    282    299       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    371    392       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    404    425       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    494    515       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    559    587       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    861    886       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    906    929       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    941    958       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1003   1025       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1117   1143       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1199   1220       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1235   1255       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1275   1295       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1386   1404       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       82    316       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      370    592       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      867   1147       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1199   1287       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1792 AA;  206755 MW;  3A6C3EF3FE5DB1A0 CRC64;
     MSLDQRKRSI MMSTSKKSLT VTKAAVISSA MLARKNSAQR GAATTRESIA ALAEMLSTAD
     IRRPHSDFLQ STMAENALKV ACIISLVTVC VHTPLTLQYF WPLTYIVFIM DFISTIILST
     EAFIRLNTYG MFSREESYFR DRWSQFDFFL LIFHWLSLLL HAYECITKLF PQMGLVYYDW
     YGVIRCVRPL IIIRLIRLVI KFKLPKSRIQ QLLKRSSQQV QNVTTFFVFF MALYAILGIQ
     VFGRMDYHCI LKGASVFTVY LAASEEGWVY VLYDCMDSLP SYWAFLYFVT LIFFLAWLVK
     NVFIAVITET FAEIRVQFSE MWQKKDVTFD DGLKQKLETT EEGWRLVKFD SEKSKNADGP
     LGLQRILRST AFQCFITGIV LINAAINASF VYRHDGTDAK RRYFYRYIES GFTILFNIEC
     IVKILCYGFR SFFKRPIFKF ELILCIGSTL NLIPYFYENN YFTLFQGFRL LRLIKASPIL
     EDFVYKIFSP GKKLGGLVIF TITFVVICTA ISLQLFCSVP KLVYFQTFPK AFMAMFQIIT
     QEGWTDFVVE VLRMIDDNMV PFVAIYFVAY HLFVTLIVLS LFVAVILDNL EMDEELKRVK
     QLKAREATTT MRTTLPWRLR VFEKFPARPA MVELKRAEND FPLPKVRDSF IHQFATDGDD
     NETDDTSEAA IIKAVMRSVP LLHHPRKEKP IVRHVGPISL KASISTMLEE SNRNRAMDAD
     TFSFATHLSR VPTRLWRKEA QRSRNKTIPT LARAKQMLFE KMTENGDLTR HSDTAPNKSQ
     KLGEIDIRAL QQKRHMAEVK RNRIEEDLRE NHLLFDRPLF FIGRDSNLRR FCKNIVYAKY
     AADFEGNGTV KSARRYKELH ALVGLMTYLD WTMVIVTSLS CISMLFESPW PTTGENLIFN
     NVYLQITDYL FVLFMTFELV VKVLANGLFF TPKAVVRDFG GVMTLFIYIT SVVFLLHMPK
     HVEINSFNQL LLIFRAMRPL RIYTLVPHIR RVVVELFRGF KEILLVTILL VVVMFIFASV
     GVQIVGGKLA ACNDPSIKHR VNCTGVFWQK IFVTRLDVYG KNDDELHPSI LVPRVWTNPR
     NFNFDHVGNG MLALFETLSY KGWNVIRDIV WQRVGPWAVV FIHIYVFIGC MIGLTLFVGV
     VVANYTENRG TALLTVDQRR WHDLKARLKM AQPLHVPPKP SESAKLRTRL YELSMSRPFA
     QIFGALVVIN SATLCIPWNV EEEAERRDND EEYKLFFATA LSAIINILFA VECLLKMIAF
     TVHGFWQSRR NRIDLLITAL GLFWVVLHFF IALPAEQLSR EAKLKKFTYT FGKEHNTQNV
     NADCGDEYVP QFLHYNSNVP LRSLLRIYWS HPFWDGKVWP GSFKRSPPMC FWAEGANYWE
     TDCGNYYGAI IYFCSFYVII TYIVRNLLVA IIMENFSLFY SSEEDALLSY ADIRNFQNVW
     NMVDVEQKRT IPVRRVKFLL RLLRERLEVD PNKDRLLFKH MCYEMERLHN GDDVSFHDVL
     YMLSYRSVDI RKSLQLEELL QREEVEYIIE EEVAKQTIRT WLEKASVSGP TFVRGGTIQP
     SVVSGGSTFL ANPPPVRPSN IQLQLEAPPA ISKIDVIEPN VFRDETSSGA DEEAGKKKKK
     SAAGRRSSIP DLMSNSLFQE AAKKFVLGGM HKKSVSTFSS KVPDVETPLK QGPISKFAAA
     ARLTTQRVES RIAQHKTSYQ TPSGLSEVEE FGEESNEASA NLDFAERRRL SVPETSQMVI
     TQFEADSIPV GSPPKVTSPR SPVFIHLAMI DDSLQKDRIN DVKSWWMEVD FE
//
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