ID U1PAE2_9EURY Unreviewed; 294 AA.
AC U1PAE2;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Lysine biosynthesis enzyme LysX {ECO:0000313|EMBL:ERH07286.1};
GN ORFNames=J07HN4v3_02925 {ECO:0000313|EMBL:ERH07286.1};
OS Halonotius sp. J07HN4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halonotius.
OX NCBI_TaxID=1070774 {ECO:0000313|EMBL:ERH07286.1, ECO:0000313|Proteomes:UP000030639};
RN [1] {ECO:0000313|EMBL:ERH07286.1, ECO:0000313|Proteomes:UP000030639}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J07HN4 {ECO:0000313|Proteomes:UP000030639};
RX PubMed=23637883;
RA Podell S., Ugalde J.A., Narasingarao P., Banfield J.F., Heidelberg K.B.,
RA Allen E.E.;
RT "Assembly-driven community genomics of a hypersaline microbial ecosystem.";
RL PLoS ONE 8:E61692-E61692(2013).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- SIMILARITY: Belongs to the RimK family. LysX subfamily.
CC {ECO:0000256|ARBA:ARBA00006239}.
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DR EMBL; KE356578; ERH07286.1; -; Genomic_DNA.
DR AlphaFoldDB; U1PAE2; -.
DR eggNOG; arCOG01589; Archaea.
DR HOGENOM; CLU_054353_2_1_2; -.
DR Proteomes; UP000030639; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013651; ATP-grasp_RimK-type.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR011870; LysX_arch.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR004666; Rp_bS6_RimK/Lys_biosynth_LsyX.
DR NCBIfam; TIGR02144; LysX_arch; 1.
DR NCBIfam; TIGR00768; rimK_fam; 1.
DR PANTHER; PTHR21621:SF2; COENZYME GAMMA-F420-2:ALPHA-L-GLUTAMATE LIGASE; 1.
DR PANTHER; PTHR21621; RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN; 1.
DR Pfam; PF08443; RimK; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000030639}.
FT DOMAIN 94..281
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 294 AA; 32004 MW; 5B52C869A1E7B7B6 CRC64;
MKLGILYSRI RQDEKLLLNE LRDRGHEIEK IDVRDQQFSL DDTTAPVDDI DLVVDRCLST
SRSLYATRFF DHYGVPVINS PETADVCADK AKNSLALDAA GVPTPETTVA FTIDSAMDAI
ESFGYPCVIK PVVGSWGRLM AKIDSESAAE AVLEHKKVLG HYEHKVFYVQ EFVDKPGRDI
RVLATDGEPV AAMTRSSDHW LTNAAKGGDT AGFELDDTAL DLVEKASDAV GGGLLGVDLM
EVGGEDSGEY TVHEINHTVE FKALNGCVET DVPATVVDWL ETKADEATPE ATVE
//
