ID U2DKD0_9BACE Unreviewed; 537 AA.
AC U2DKD0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF1981_02753 {ECO:0000313|EMBL:ERI81987.1};
OS Bacteroides pyogenes F0041.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1321819 {ECO:0000313|EMBL:ERI81987.1, ECO:0000313|Proteomes:UP000016496};
RN [1] {ECO:0000313|EMBL:ERI81987.1, ECO:0000313|Proteomes:UP000016496}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0041 {ECO:0000313|EMBL:ERI81987.1,
RC ECO:0000313|Proteomes:UP000016496};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERI81987.1}.
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DR EMBL; AWSV01000145; ERI81987.1; -; Genomic_DNA.
DR RefSeq; WP_021646384.1; NZ_KE993143.1.
DR AlphaFoldDB; U2DKD0; -.
DR PATRIC; fig|1321819.3.peg.2543; -.
DR HOGENOM; CLU_007082_5_1_10; -.
DR OrthoDB; 1090159at2; -.
DR Proteomes; UP000016496; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 25..146
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 149..499
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 316
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 537 AA; 60851 MW; C1AE12497A6C9E71 CRC64;
MNKPIVLFVM LLFALGVAAQ EHLSALLPFP NYVEQRQGVF RLSNKETIGV GSGDLRFAAA
ELQQVFKQRF GFAPAVADNG RIRLMLNPRM EGEEQYRLTV DAKGISIEGR TAAGVYYGVM
TLDQLLLGDV ANTKQGRIQA VRIDDAPAYP FRALMLDPAR HFLPVEAVKG YIDCMAHYKF
NTLQLHLSDD QGWRIEIKSH PKLTEVGAFR NPKAPAISPD NGYYTQQQLR ELVEYAALRN
VEIIPEIDVP GHTAAILTAY PDLRCDFLKD SAFVFGKTDN VMLSAANPKV YEVLDDIIRE
VGDVFPSKKI HLGGDESAIE RNWAKSPENL ELMRSHGYTS PDQLMNVFFG KVLASAKKYG
LHAMLWCELD NIRLPADKYL FDYPQDVTLV TWRYGLTPKC IELTRESGNT LILAPGEYTY
FDYPQYANDL PEFNNWGMPL TTLRKTYEFD PTYKLEPGQR KHIAGVMGTL WGEAIKDINR
ANYMTYPRGL ALSEAGWTRM SLRSWDSFRK RLYPNLSELM KRGVSFRVPF EIAGEGR
//
