ID   U2J0I4_9PORP            Unreviewed;       344 AA.
AC   U2J0I4;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Thiamine pyrophosphate enzyme, TPP binding domain protein {ECO:0000313|EMBL:ERJ73265.1};
GN   ORFNames=HMPREF1556_00138 {ECO:0000313|EMBL:ERJ73265.1};
OS   Porphyromonas sp. oral taxon 278 str. W7784.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC   Porphyromonas.
OX   NCBI_TaxID=1227272 {ECO:0000313|EMBL:ERJ73265.1, ECO:0000313|Proteomes:UP000016628};
RN   [1] {ECO:0000313|EMBL:ERJ73265.1, ECO:0000313|Proteomes:UP000016628}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W7784 {ECO:0000313|EMBL:ERJ73265.1,
RC   ECO:0000313|Proteomes:UP000016628};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Warren W., Mitreva M., Mardis E.R.,
RA   Wilson R.K.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERJ73265.1}.
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DR   EMBL; AWUX01000016; ERJ73265.1; -; Genomic_DNA.
DR   RefSeq; WP_021666483.1; NZ_KI259224.1.
DR   AlphaFoldDB; U2J0I4; -.
DR   STRING; 1227272.HMPREF1556_00138; -.
DR   PATRIC; fig|1227272.3.peg.108; -.
DR   eggNOG; COG1013; Bacteria.
DR   HOGENOM; CLU_048564_1_0_10; -.
DR   OrthoDB; 9775140at2; -.
DR   Proteomes; UP000016628; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   CDD; cd03375; TPP_OGFOR; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          56..203
FT                   /note="Thiamine pyrophosphate enzyme TPP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02775"
SQ   SEQUENCE   344 AA;  37774 MW;  DE274562CAEC0973 CRC64;
     METNANPVKL DAKNFKSDQY VRWCPGCGDH GVLATLQKSM AEVGIPTEKT AVISGIGCSS
     RLPYYVNAYG FHTIHGRAAA IATGLKTARP DLCVWIATGD GDSLAIGGNH FIHAIRRNVD
     LNFILFNNRI YGLTKGQYSP TSARGFVSKS SPFGTVEDPF IPAELCFGAR GRFFARSLDI
     DMKLLGQCMV ASAKHKGASV VEVLVNCVIF NDGIHKGVAQ REVRDDRSII LRHGEKMIFG
     KEKNKGIVLD GLRLKAVTIG EDGYTLDDVL THDAHEVDPT LHTMLAMMGT NDDMPVAFGV
     IREVEDICYD QAVTDQIEEV RAQKPGIRSL EDVLLKDAYW EVKE
//