ID   U2JN63_9FIRM            Unreviewed;       291 AA.
AC   U2JN63;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Ketopantoate reductase PanE/ApbA {ECO:0000313|EMBL:ERJ81275.1};
GN   ORFNames=HMPREF1987_01808 {ECO:0000313|EMBL:ERJ81275.1};
OS   Peptostreptococcaceae bacterium oral taxon 113 str. W5053.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX   NCBI_TaxID=1321784 {ECO:0000313|EMBL:ERJ81275.1, ECO:0000313|Proteomes:UP000016618};
RN   [1] {ECO:0000313|EMBL:ERJ81275.1, ECO:0000313|Proteomes:UP000016618}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W5053 {ECO:0000313|EMBL:ERJ81275.1,
RC   ECO:0000313|Proteomes:UP000016618};
RA   Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA   O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA   Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERJ81275.1}.
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DR   EMBL; AWVB01000115; ERJ81275.1; -; Genomic_DNA.
DR   AlphaFoldDB; U2JN63; -.
DR   STRING; 1321784.HMPREF1987_01808; -.
DR   PATRIC; fig|1321784.3.peg.1695; -.
DR   eggNOG; COG1893; Bacteria.
DR   HOGENOM; CLU_055593_2_0_9; -.
DR   Proteomes; UP000016618; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013332; KPR_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF02558; ApbA; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016618};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        238..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..118
FT                   /note="Ketopantoate reductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02558"
SQ   SEQUENCE   291 AA;  33451 MW;  9C21BC3C328C89B0 CRC64;
     MLIYGAGVIG SLYATLFSQA GYDVTVYARG KRLEALKEKG LIFLKKEKQY YAKVHIISKL
     FCEDTYDFIF LTVKGHQVYE ALRELKENQS NTIVTMVNSL DDYDSWENIC GKGRILPAFP
     GAGGSIEENV LDASLTPGMI QKTSFAEIGG ENSERVRKLQ TIFQRSRIPY QIVPDMHIWQ
     ICHLAVVVPI GDAYYETECP QKVGKNFRQM LETARQIKEN CKKLYRSGMK LSPGKINLFR
     VLPVFFLGVG LSVLFNSNFG DKFMYRHSMK APDEMKQLHR WFYEYLSQRE N
//