ID   U2KQ46_9BACT            Unreviewed;       513 AA.
AC   U2KQ46;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Type I phosphodiesterase/nucleotide pyrophosphatase {ECO:0000313|EMBL:ERK00587.1};
GN   ORFNames=HMPREF1218_0518 {ECO:0000313|EMBL:ERK00587.1};
OS   Hoylesella pleuritidis F0068.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Hoylesella.
OX   NCBI_TaxID=1081904 {ECO:0000313|EMBL:ERK00587.1, ECO:0000313|Proteomes:UP000016600};
RN   [1] {ECO:0000313|EMBL:ERK00587.1, ECO:0000313|Proteomes:UP000016600}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0068 {ECO:0000313|EMBL:ERK00587.1,
RC   ECO:0000313|Proteomes:UP000016600};
RA   Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA   Methe B., Sutton G., Nelson K.E.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- PTM: The conversion to 3-oxoalanine (also known as C-formylglycine,
CC       FGly), of a serine or cysteine residue in prokaryotes and of a cysteine
CC       residue in eukaryotes, is critical for catalytic activity.
CC       {ECO:0000256|PIRSR:PIRSR600917-52}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERK00587.1}.
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DR   EMBL; AWET01000036; ERK00587.1; -; Genomic_DNA.
DR   AlphaFoldDB; U2KQ46; -.
DR   PATRIC; fig|1081904.3.peg.1554; -.
DR   Proteomes; UP000016600; Unassembled WGS sequence.
DR   CDD; cd16034; sulfatase_like; 1.
DR   Gene3D; 3.30.1120.10; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR42693:SF33; ARYLSULFATASE; 1.
DR   PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016600}.
FT   DOMAIN          31..382
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   MOD_RES         90
FT                   /note="3-oxoalanine (Ser)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600917-52"
SQ   SEQUENCE   513 AA;  58517 MW;  278BF60373AAC868 CRC64;
     MKTFNLLISS LAIIPQIGMA KKVKTQPLQR PNVIYVFPDQ FRNFAMGFWR QEGFRDQLRT
     TGDPVLTPNL DRFAREAVVL SSAMSNCPLS SPHRGSLLTG MYPNKSGITL NCNSNRPNSS
     LRDDAECISD VMSKAGYDCG YIGKLHAHYP TPNDPQRPGH YVENRIPAWD AYTPKERRHG
     FNYWYSYGTF DVHKNPHYWD TNGMKHEPHE WSPLHEAQKA IDYIRNKDNV RDPRKPFLLM
     VGMNPPHSPY RSMSDCMEED YALYRDKPID SLLIRPNVDK TLEKAASARF YFASVSGVDR
     AFGQILAALK EAGLDKNTIV IFSSDHGETM CSQNTEDPKN SPYAESMNVP FIVRYPGKMA
     PRVDNLLLSS PDIMPTILGM VGLGKRIPTE VQGKDYSALF FDKNARVQRP GGALYIQNVN
     GDKNAEGKIV SYFPSARGIK TADYTLAIYI NKKHQIKEVL FFDDKNDPYQ MHNLKPEDHP
     DIVKHLYAQM GQMLKEIDDP WYKKRILSNM IPY
//