ID U2PQV5_9CLOT Unreviewed; 655 AA.
AC U2PQV5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ERK28820.1};
GN ORFNames=CINTURNW_3935 {ECO:0000313|EMBL:ERK28820.1};
OS Clostridium intestinale URNW.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1294142 {ECO:0000313|EMBL:ERK28820.1, ECO:0000313|Proteomes:UP000016721};
RN [1] {ECO:0000313|EMBL:ERK28820.1, ECO:0000313|Proteomes:UP000016721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=URNW {ECO:0000313|EMBL:ERK28820.1,
RC ECO:0000313|Proteomes:UP000016721};
RX PubMed=24136853;
RA Lal S., Ramachandran U., Zhang X., Sparling R., Levin D.B.;
RT "Draft Genome Sequence of the Hydrogen- and Ethanol-Producing Bacterium
RT Clostridium intestinale Strain URNW.";
RL Genome Announc. 1:e00871-13(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK28820.1}.
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DR EMBL; APJA01000028; ERK28820.1; -; Genomic_DNA.
DR RefSeq; WP_021803843.1; NZ_KI273145.1.
DR AlphaFoldDB; U2PQV5; -.
DR STRING; 1294142.CINTURNW_3935; -.
DR PATRIC; fig|1294142.3.peg.4093; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_19_9; -.
DR OrthoDB; 13222at2; -.
DR Proteomes; UP000016721; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016721};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 298..350
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 369..626
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 655 AA; 71953 MW; F9FD97F5FAFF0A6C CRC64;
MTKRTHIIGI RYKLMTSLLS ICLVPLLVLG IGSYLQARSS LIDKFEISSE QVIPEVIEKF
NKYPVQISMA SSNTILMDSK SEQKDIKDYL QKFKERNEDV LNVFFYTEKG EIFSYPDEKK
ATNPKGEVWY EKAINNNGKV INSDPHKSLI ADESVVTFAK TVEDKGKIVG VIGMEISINK
LSSITNKYRI GNKGYIFVVN EEGNVVTYPS RIIGSDSDTK ISNWDVIKNN ENGSTEIDFN
KSHIFTTFGT DSGTGFKIIA AMDESELKAD ISGIKNMIFI TIGAVIVIAA LFSFWLSNGL
AKSAKKLEQG FKKAAEGDLT VKVDIKSKDE FGELGKNFNF MIKNMSALML EVKNSSKTVF
DTSTNLGIMA EESTASVGQV YNSIEEISRG IIGQAGSAQE GASNINELSK EIDGIVENTK
VLKSVSLNAL ELGNKGLNMV KVLGEKSDRS KISSNEASKI VLNMNKNTEE INRISDAIKE
ITEQTNLLSL NASIEAARAG EAGRGFAVVA DEIRKLADQS RKSTEEIRKI IEKVQSMSKV
AISAMEESKV TVEEQEVAVN ETEKIFTQIL DAINQLTNRI KGIAESTSEI YSKKNKVVQK
IESISEISEG TAASSEEVAA STEQINTTMD EVAKGVEELS LIASNLQYAV GKFKL
//
