ID U2QHW4_9BACT Unreviewed; 853 AA.
AC U2QHW4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Chain length determinant protein {ECO:0000313|EMBL:ERK38402.1};
GN ORFNames=HMPREF9135_0857 {ECO:0000313|EMBL:ERK38402.1};
OS Segatella baroniae F0067.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Segatella.
OX NCBI_TaxID=1115809 {ECO:0000313|EMBL:ERK38402.1, ECO:0000313|Proteomes:UP000016648};
RN [1] {ECO:0000313|EMBL:ERK38402.1, ECO:0000313|Proteomes:UP000016648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0067 {ECO:0000313|EMBL:ERK38402.1,
RC ECO:0000313|Proteomes:UP000016648};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK38402.1}.
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DR EMBL; AWEY01000039; ERK38402.1; -; Genomic_DNA.
DR RefSeq; WP_021590664.1; NZ_AWEY01000039.1.
DR AlphaFoldDB; U2QHW4; -.
DR PATRIC; fig|1115809.3.peg.2299; -.
DR Proteomes; UP000016648; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016648};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 34..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..113
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 457..534
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 602..756
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
SQ SEQUENCE 853 AA; 95504 MW; F57A0D936827CAD2 CRC64;
MEENKNVVPE KMLEQEERSS FDFQAIYTMV VLNWKWFVLS LMICLGAAYI YLRYATPMYQ
AYAKLLIKDD DNKRRGNSIE NAVNLGLISN SNGIDNEIEL LASHSLAQAA VRDMKIYTNY
FVEGNIRSQE LYHTQPFNVD LDAAHLDRLN RPVDMTIEKV GSGYNIVGKY FVPRSEGRAG
GPYDIDKRVT RIPALVNTRI GVIRITRNML SPMQDLNDRQ VLKVRLMSPK MAAAKYIKNL
TVNQTSKTTT IAQLTLRDEL PQRATDYLKQ LAIVYNRQAN EDKNEVAQKT EAFINSRLEK
INAELGSTEG TLENYKRRNN MVELKMNAGQ AVANQDVFAQ KLAEANMQVA LLNEMSLYMN
QPGNKYEALP SNVGLNDQNA TALINKYNEI AMDRKRLLRS ASETSPTVTP LTAQLDDLGN
SIRRAMNQSR RNMEIQRNSV AAQFSKYSGD VGATPEQERM LTQIGRQQEV KSGLYLMLLQ
KREENSISLA ATADKGKLID DPECDGKVSP KSAIIFLIAF VLGLGMPVVV IFVLQFFSYR
IEGHMDVIRL TKLPIIADIP VASETSKTKA DIVVHENKNN LMEEIFRSLR TNLQFILKGD
EKVIAFTSTT SGEGKTFTAS NLAVSFALLG RKVILVGLDI RKPRLAELFE IDDHQHGITN
LLIQANPTEQ DIRKQILASG INHNLELLMA GPTPPNPAEL LTRTSLDSIF EQLRQMYDYV
IVDTAPVGLV TDTLQIARVT DATVVMTRAD YTAKESVGLV NSLADGNKLP NVCIVINGID
MSKKKHGYYY GYGKYAKYGR YARLGGSYGN YGRYGGYGAY GSYGRYGSYG SYGSYGNYSN
SHYGDKNDDS IKK
//
