ID U2QV14_9BACL Unreviewed; 375 AA.
AC U2QV14;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=HMPREF1983_00332 {ECO:0000313|EMBL:ERK60039.1};
OS Gemella bergeri ATCC 700627.
OC Bacteria; Bacillota; Bacilli; Bacillales; Gemellaceae; Gemella.
OX NCBI_TaxID=1321820 {ECO:0000313|EMBL:ERK60039.1, ECO:0000313|Proteomes:UP000016637};
RN [1] {ECO:0000313|EMBL:ERK60039.1, ECO:0000313|Proteomes:UP000016637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700627 {ECO:0000313|EMBL:ERK60039.1,
RC ECO:0000313|Proteomes:UP000016637};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK60039.1}.
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DR EMBL; AWVP01000018; ERK60039.1; -; Genomic_DNA.
DR RefSeq; WP_021752693.1; NZ_KI271818.1.
DR AlphaFoldDB; U2QV14; -.
DR PATRIC; fig|1321820.3.peg.325; -.
DR eggNOG; COG0116; Bacteria.
DR HOGENOM; CLU_032119_3_1_9; -.
DR Proteomes; UP000016637; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 43..154
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 375 AA; 42886 MW; 15DB63E22819E4A4 CRC64;
MKYNLVATTP MGIEAIVAKE VQELGYDTKV ENGRVYYSGD KRAIVKSNLW LRCADRVKIV
VAQFPAYTFE ELFEKTKEIE WDKYLPVDAK FPVDGRSHKS TLFSVSDCQS IVKKAIVEKM
KKSYGITGWL TETGARYRLE IIMLNDIATI LLDTSGDGLH KRGYRAKQGT APLKETLAAA
MVKLMNWKGE TPLYDVFCGS GTLLIEAAML AQNMAPGINR NFDFEKWPWI PKALVDEERN
NAEEAIDYEK ELELYGSDID PKMIATAENN AEEIGLAGVI NFKQMSVYDF VVKKEVGCVI
ANPPYGERLG EKKEVEAMYK YLGEALKDRR YWSLYLLTSN KMFEHLYGKK ATKRRKLFNG
SIECTYYQYW GEKIR
//
