ID U2RWA0_LEIAQ Unreviewed; 425 AA.
AC U2RWA0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Cytosol aminopeptidase family, catalytic domain protein {ECO:0000313|EMBL:ERK73026.1};
DE Flags: Fragment;
GN ORFNames=N136_00608 {ECO:0000313|EMBL:ERK73026.1};
OS Leifsonia aquatica ATCC 14665.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leifsonia.
OX NCBI_TaxID=1358026 {ECO:0000313|EMBL:ERK73026.1, ECO:0000313|Proteomes:UP000016605};
RN [1] {ECO:0000313|EMBL:ERK73026.1, ECO:0000313|Proteomes:UP000016605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14665 {ECO:0000313|EMBL:ERK73026.1,
RC ECO:0000313|Proteomes:UP000016605};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M17 family.
CC {ECO:0000256|ARBA:ARBA00009528}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK73026.1}.
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DR EMBL; AWVQ01000058; ERK73026.1; -; Genomic_DNA.
DR RefSeq; WP_021764234.1; NZ_KI272436.1.
DR AlphaFoldDB; U2RWA0; -.
DR PATRIC; fig|1358026.3.peg.525; -.
DR HOGENOM; CLU_013734_2_2_11; -.
DR OrthoDB; 9809354at2; -.
DR Proteomes; UP000016605; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00433; Peptidase_M17; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR011356; Leucine_aapep/pepB.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR000819; Peptidase_M17_C.
DR InterPro; IPR008283; Peptidase_M17_N.
DR PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11963:SF23; ZGC:152830; 1.
DR Pfam; PF00883; Peptidase_M17; 1.
DR Pfam; PF02789; Peptidase_M17_N; 1.
DR PRINTS; PR00481; LAMNOPPTDASE.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00631; CYTOSOL_AP; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW ECO:0000313|EMBL:ERK73026.1}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000016605}.
FT DOMAIN 261..268
FT /note="Cytosol aminopeptidase"
FT /evidence="ECO:0000259|PROSITE:PS00631"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ERK73026.1"
SQ SEQUENCE 425 AA; 43205 MW; AF1D0C594158E6B7 CRC64;
LAVIGLGDDL DGDALRYAAG SAIRQLAGTP RVTVELPAES DSLLGAVIEG AALGSYSYTE
YREKSTAKSP VSAITVIGEP SEAAGDDLLA RAAAVAGAAS LVKDLVNMPP LDLYPETFAE
RAQEAAAGLP VDITVWDEAA LAEGGFGGIL GVGQGSTRPP RLVKVDYAPA GASPHLALVG
KGITFDSGGL SLKPASGMVG MKYDMTGAAT VLAVAIAAAQ LALPVRVTAW LCLAENMPSG
SAIRPNDVLR IRDGRTVEVL NTDAEGRLVL ADGLAAASEE HPDAIVDVAT LTGAAMVALG
TRYAAVMGSD DLVDEVLAAS RASGELLWPM PLSGELRATI NSDVADIANA NPGQTAGGML
LAGVFLQEFV GRTGDGDDAP RIPWAHLDIA GPAKGPASPY GFTGKGASAV SVRALVRLAE
DFSRK
//
