ID U2TEK9_9FIRM Unreviewed; 804 AA.
AC U2TEK9;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=DNA internalization competence protein ComEC/Rec2-like protein {ECO:0000313|EMBL:ERL04648.1};
GN ORFNames=HMPREF1985_01429 {ECO:0000313|EMBL:ERL04648.1};
OS Mitsuokella sp. oral taxon 131 str. W9106.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Mitsuokella.
OX NCBI_TaxID=1321781 {ECO:0000313|EMBL:ERL04648.1, ECO:0000313|Proteomes:UP000016614};
RN [1] {ECO:0000313|EMBL:ERL04648.1, ECO:0000313|Proteomes:UP000016614}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W9106 {ECO:0000313|EMBL:ERL04648.1,
RC ECO:0000313|Proteomes:UP000016614};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL04648.1}.
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DR EMBL; AWVT01000011; ERL04648.1; -; Genomic_DNA.
DR RefSeq; WP_021771686.1; NZ_KI273058.1.
DR AlphaFoldDB; U2TEK9; -.
DR STRING; 1321781.HMPREF1985_01429; -.
DR PATRIC; fig|1321781.3.peg.1344; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_2_1_9; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000016614; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR000424; Primosome_PriB/ssb.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR PROSITE; PS50935; SSB; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00252};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016614};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 520..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 551..753
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 804 AA; 85998 MW; E85AF7D356AD3D12 CRC64;
MEQGQHPKCF AAGLLLVLAL GIYAAHAAFF PVMPLCIVLG ILFLLSAFLA WRSSRWTFLS
FLLLFFVLGI VRGAMGFSLP ANDISHIPGS DVKVRGILRE APQESMNGRG EARSRYRIEV
TEVKRPRDED WKTASGGLRI YAQGAAKEAQ IGDRVTASGN LRLPHSYRNE GQIDTVLLLR
ADGITASLMA KASQVKIESR DAGWRDAVLR IGTRLRAHYF ETMQKSMARP DAAALFAMLF
GGYDGIKESL VDSFVTTGLV HILSVSGSHV SLLAATIAWL GLLLRLPRPL TAGLVLLAVA
FYVILAGCVP PAVRSGVMGG LAFIALAIDR EHEGQYIMLL TGMLMLAASP LLLFHISFQL
SFAATAGLLF LAPVFRTWMK AHGLPNFAAA GLSITLAAQL ATLPLLAYYF GRVSLVAFLA
NLILVPPVEL LIVIALFGGM AALALPILGQ LVFALLGLLL GFVYELARKL SGMPLAMVGV
SAMGAGKTAC YYLALSFLLF PDCLRNRLRE YASLFHRREV CAIASVSLLL LLLHAVLAPK
TMEVHFLDVH QGDACLIKTP HGHAFFIDTG GTRDGAYDVG KQIDVPYLRR NGIRSLDAIF
LSHAHEDHAA GAGGILRELP VYHVYTASEG RNVYAKSMGM SIADPLLDTL TPLCTGERFA
IDGVTVDVLF APAAAQMNGS GNEACDVLRV SYGDVSILFT GDMEEPEEHD LLAHGIDPAS
TVLKVGHHGA ATSTSGAFLR AVAPKLAVIS VGADNTYGHP APAVLARLEA QGASVLRTDE
QGAVILTTDG KGVQVKTYIG ATVP
//
