ID U2UL07_9FUSO Unreviewed; 1090 AA.
AC U2UL07;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Helicase protein {ECO:0000313|EMBL:ERL25629.1};
GN ORFNames=HMPREF9108_01810 {ECO:0000313|EMBL:ERL25629.1};
OS Leptotrichia sp. oral taxon 225 str. F0581.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Leptotrichiaceae;
OC Leptotrichia.
OX NCBI_TaxID=1321774 {ECO:0000313|EMBL:ERL25629.1, ECO:0000313|Proteomes:UP000016631};
RN [1] {ECO:0000313|EMBL:ERL25629.1, ECO:0000313|Proteomes:UP000016631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0581 {ECO:0000313|EMBL:ERL25629.1,
RC ECO:0000313|Proteomes:UP000016631};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL25629.1}.
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DR EMBL; AWVS01000133; ERL25629.1; -; Genomic_DNA.
DR RefSeq; WP_021768584.1; NZ_KI272921.1.
DR AlphaFoldDB; U2UL07; -.
DR PATRIC; fig|1321774.3.peg.1727; -.
DR eggNOG; COG1061; Bacteria.
DR eggNOG; COG3886; Bacteria.
DR HOGENOM; CLU_005588_1_1_0; -.
DR Proteomes; UP000016631; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:UniProt.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR021835; DUF3427.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF11907; DUF3427; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50035; PLD; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:ERL25629.1};
KW Helicase {ECO:0000313|EMBL:ERL25629.1};
KW Hydrolase {ECO:0000313|EMBL:ERL25629.1};
KW Nucleotide-binding {ECO:0000313|EMBL:ERL25629.1}.
FT DOMAIN 193..223
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 311..482
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 525..689
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1090 AA; 128448 MW; 1F053F3834180853 CRC64;
MSILVKKSEP NNLINTEEKN DNFLEITEYK ENLEFEVLET FSEKISDFIG KNDYQKVIEF
TEKQLYLLNQ AFTDKSEKIK TQNTDFHFEL PLKRKNSDII GNINELIINE KVKFRNFFIY
LKQELLNCKK FYFIVSFIKY SGIQLLISTL DELEKQGIQG EIITSVYLNI TDSKALRKLL
SYKNIKVKIY NNSSESFHTK AYLFEKEKYH SVIIGSSNIS QSALYSAEEW NVKLTDSSFF
NIYKKSLNQF EKLWHSNEAI ELTEDFIDEY EKYKKSINTQ NTFDYRKTKI TQKDEFIPNS
MQKRVLEKLK ETRENGNKKG LVISATGTGK TYLAAMDIKQ FFEINSNNKN KLFETNEGKS
KILNIKFLFI AHREELLENA INVFSRILKI DKNEFGRIYG GLKEINKSMI FASIQSLRNC
YNEFKPDFFN YIIVDEFHHS MSDSYLKTLS YFQSKFLLGL TATPKRMDGK DILSLCDYNV
VDEIGIKEAL EEDLIVPFHY FGVNDYMINY DNIPYKNGKY NEKVLLENLL LNTRTDYIVE
KINKFGFDGD KLSAVAFCQN IEHAFFMKEE FTNKSYKSAV ITANTSSNER SEILDKFKNK
KIEILCVVDI LNEGIDIPTI NLLLFLRPTM SSTIFIQQIG RGLRKAENKD FVTIIDFIGN
HKKDYLLINY FSNEVDNKDT LFTKKEKIIN EIKNQFSNIP KSCYVELDRV CQNRIIEKIE
KINFSSKNIL KDLYLDYKEE IGKSENEILK VSDFDTNIEL FQELSLKLGS FYNAQLQFEN
PEILKMNKIS LNSEEIEFLA YLEKKLMLVE PFTYLIINYL INNEFITSEI TINEYKNYFN
IKNDFEKEYV INRIFRELVE DKILEQNSKN NNLFKISENY RKIFQNIDKI NNNNKINLKI
INLDNSQNSN YNFKIRLKEL LYLGLSEFKK SNNLSIFNEN ILIPYKKYKR IELQILLDSK
VPKGSWRAGY ANTDKDICLF ATIDKTHILQ ENLKYDNSLF ADNIIQWISQ PKTAHNSSVG
KMFTNHSELG YNVYIFIRKY AFMNNNKTNP FIYLGKANYY KSYGDKPMRI LWKLDEKIPQ
ELIYELYNLS
//
