ID U2URF3_9FIRM Unreviewed; 619 AA.
AC U2URF3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=DNA (Cytosine-5-)-methyltransferase {ECO:0000313|EMBL:ERL05697.1};
GN ORFNames=HMPREF1985_00632 {ECO:0000313|EMBL:ERL05697.1};
OS Mitsuokella sp. oral taxon 131 str. W9106.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Mitsuokella.
OX NCBI_TaxID=1321781 {ECO:0000313|EMBL:ERL05697.1, ECO:0000313|Proteomes:UP000016614};
RN [1] {ECO:0000313|EMBL:ERL05697.1, ECO:0000313|Proteomes:UP000016614}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W9106 {ECO:0000313|EMBL:ERL05697.1,
RC ECO:0000313|Proteomes:UP000016614};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL05697.1}.
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DR EMBL; AWVT01000007; ERL05697.1; -; Genomic_DNA.
DR RefSeq; WP_021770439.1; NZ_KI273050.1.
DR AlphaFoldDB; U2URF3; -.
DR STRING; 1321781.HMPREF1985_00632; -.
DR PATRIC; fig|1321781.3.peg.606; -.
DR eggNOG; COG2189; Bacteria.
DR HOGENOM; CLU_020164_2_1_9; -.
DR OrthoDB; 9800801at2; -.
DR Proteomes; UP000016614; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR002295; N4/N6-MTase_EcoPI_Mod-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF16; TYPE III RESTRICTION-MODIFICATION ENZYME STYLTI MOD SUBUNIT; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PIRSF; PIRSF015855; TypeIII_Mtase_mKpnI; 1.
DR PRINTS; PR00506; D21N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ERL05697.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016614};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ERL05697.1}.
FT DOMAIN 111..420
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 619 AA; 70904 MW; FE7B68BC9233CDE4 CRC64;
MKKLAGESLN IMEENLAAMQ QLFPEAFEEG KIDFDVLRQL LGDYVDDEEE RYSFRWNGKG
KALRLSQTPS TGTLRPCKEE SKDWNTTENL YIEGDNLEVL KLLQKSYHGK VKMIYIDPPY
NTGKDFVYKD DFRDNVANYK RITGQVDDEG KPIGTQKESD GKFHTNWLNM IYPRLRLARN
LLCEDGVLFI SIDYNENFNM RLVANSVFGE NHFIGEIYWE SKTKSQNTQT SYNKLQPKEE
MILVYSRQEK RRFHLLERSI KEYPERDERG AFRCYPIEVM NATGVRGRES MIFEISDGVS
TVCPPAGKQW KLGQDQVATY KDAGDLYIKR GKAIIKMRPE YERTETTEPF WGFFSKEMGT
AESAKKELNV LVSHNGFDTV KPVAIIERLM YHAMDNQDIV LDFFSGSATT AHAVMNLNAE
DGGNRRFILV QLPETTPVDS EARKAGYENI CEIGKERIRR AGEKIKAECE DAERAASLDI
GFKVFKLDSS NLQKWQPQPE DLLASLQESM DNFLPDRTNL DVVYEIALKL GLDLSYEVEE
READGQTIYV IGAGALMICL DSQISAETAE ALLKLHEEYK PETWQVVFRD TGFLSDQEKT
NIKETLKSAG LDEDAFISI
//
