ID U2WE76_9PROT Unreviewed; 353 AA.
AC U2WE76;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Acetolactate synthase I-II-III large subunit protein {ECO:0000313|EMBL:ERL47799.1};
DE EC=2.2.1.6 {ECO:0000313|EMBL:ERL47799.1};
GN ORFNames=RS24_00779 {ECO:0000313|EMBL:ERL47799.1};
OS Candidatus Micropelagos thuwalensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; PS1 clade; Micropelagos.
OX NCBI_TaxID=1397666 {ECO:0000313|EMBL:ERL47799.1, ECO:0000313|Proteomes:UP000016762};
RN [1] {ECO:0000313|EMBL:ERL47799.1, ECO:0000313|Proteomes:UP000016762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS24 {ECO:0000313|EMBL:ERL47799.1,
RC ECO:0000313|Proteomes:UP000016762};
RX PubMed=24785133; DOI=10.1111/1574-6941.12348;
RA Jimenez-Infante F., Ngugi D.K., Alam I., Rashid M., Baalawi W., Kamau A.A.,
RA Bajic V.B., Stingl U.;
RT "Genomic differentiation among two strains of the PS1 clade isolated from
RT geographically separated marine habitats.";
RL FEMS Microbiol. Ecol. 89:181-197(2014).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|PIRSR:PIRSR600715-1};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL47799.1}.
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DR EMBL; AWXE01000001; ERL47799.1; -; Genomic_DNA.
DR RefSeq; WP_021776816.1; NZ_AWXE01000001.1.
DR AlphaFoldDB; U2WE76; -.
DR STRING; 1397666.RS24_00779; -.
DR PATRIC; fig|1397666.3.peg.708; -.
DR eggNOG; COG0472; Bacteria.
DR OrthoDB; 9783652at2; -.
DR Proteomes; UP000016762; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003984; F:acetolactate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR CDD; cd06853; GT_WecA_like; 1.
DR InterPro; IPR000715; Glycosyl_transferase_4.
DR PANTHER; PTHR22926; PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE; 1.
DR PANTHER; PTHR22926:SF3; UNDECAPRENYL-PHOSPHATE ALPHA-N-ACETYLGLUCOSAMINYL 1-PHOSPHATE TRANSFERASE; 1.
DR Pfam; PF00953; Glycos_transf_4; 1.
PE 4: Predicted;
KW Magnesium {ECO:0000256|PIRSR:PIRSR600715-1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR600715-1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ERL47799.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT BINDING 154
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR600715-1"
FT BINDING 218
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR600715-1"
SQ SEQUENCE 353 AA; 39164 MW; C6BBB6E8E3FC28D1 CRC64;
MSNDNNWMLL AALTGVLTLF AIFCLIPMAK KIGLVDKPGG RKKHLGEIPL IGGISIFLVL
GTFAVFTGYF NNDWKWVLGV ASILIIIGLI DDLWDIRPLY KLGAQIIAAI LMVFSTGDFI
QTIAYLPSGH TINIAELGYF ITLFAVVGLI NAFNMMDGID GLAATQAILS IVLTFTSMFI
LKTTFSNDIF IIFLLGALLG FLIANLNLLP KTKVFLGDAG SMMLGFFIAW MLISYTQTPN
KQGLPPSLAL WVVAIPVADT LALSVRRILL RRSPFRPDRK HLHHICLRLG LSPLHSLAII
CMLSIISYLI GISTYLLFGE IASIILFFVM IGLYYKFIKN IWRISSLFRR LIN
//
