ID U2YDV4_STRAP Unreviewed; 347 AA.
AC U2YDV4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component {ECO:0000313|EMBL:GAD45565.1};
GN ORFNames=ANG6_0060 {ECO:0000313|EMBL:GAD45565.1};
OS Streptococcus anginosus T5.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus; Streptococcus anginosus group.
OX NCBI_TaxID=1163302 {ECO:0000313|EMBL:GAD45565.1, ECO:0000313|Proteomes:UP000016981};
RN [1] {ECO:0000313|EMBL:GAD45565.1, ECO:0000313|Proteomes:UP000016981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T5 {ECO:0000313|EMBL:GAD45565.1,
RC ECO:0000313|Proteomes:UP000016981};
RA Maruyama F., Sakurai A., Ogura Y., Homma H., Takahashi N., Ohtsubo Y.,
RA Hoshino T., Okahashi N., Nakagawa I., Kimura S., Fujiwara T., Hayashi T.,
RA Shintani S.;
RT "Genome Sequences of seven clinical isolates and type strains of anginosus
RT group streptococci.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
CC -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00007317}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD45565.1}.
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DR EMBL; BASY01000001; GAD45565.1; -; Genomic_DNA.
DR RefSeq; WP_022525849.1; NZ_BASY01000001.1.
DR AlphaFoldDB; U2YDV4; -.
DR Proteomes; UP000016981; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 4.10.320.10; E3-binding domain; 2.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR036625; E3-bd_dom_sf.
DR InterPro; IPR004167; PSBD.
DR PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 1.
DR Pfam; PF02817; E3_binding; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR SUPFAM; SSF47005; Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex; 2.
DR PROSITE; PS51826; PSBD; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:GAD45565.1};
KW Pyruvate {ECO:0000313|EMBL:GAD45565.1};
KW Transferase {ECO:0000313|EMBL:GAD45565.1}.
FT DOMAIN 7..44
FT /note="Peripheral subunit-binding (PSBD)"
FT /evidence="ECO:0000259|PROSITE:PS51826"
FT DOMAIN 50..87
FT /note="Peripheral subunit-binding (PSBD)"
FT /evidence="ECO:0000259|PROSITE:PS51826"
SQ SEQUENCE 347 AA; 38179 MW; F90D1FEEED15B1B6 CRC64;
MDDKKLRATP AARKLADDLG INLYDVSGTG AKGRVHKEDI ESYRESNIVK ITPLAKRIAE
ENNIAWQEIQ GTGVHGKIMK KDILALLPEN VDSDSIKSPA QIEKTEEIPD NITPYGEIER
LPMTPMRKVI AQRMVDSYLT APTFTLNYDV DMTELLALRK KVLEPIMEAT GKKITVTDLL
SMAVVKILMK HPYLNSSLTE DGQTVIMHNY VNLAMAVGMD NGLMTPVVYN AEKMSLSELV
VAFKDVIERT LNGKLAPSEL QNSTFTISNL GMFGVQSFGP IINQPNSAIL GVSSTIEKPV
VVNGEIVIRP IMSLGLTIDH RVVDGMAGAK FMKDLKALIE DPISMLV
//
