ID   U3D5A3_CALJA            Unreviewed;       532 AA.
AC   U3D5A3;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Polypyrimidine tract-binding protein 2 {ECO:0000313|EMBL:JAB33658.1};
GN   Name=PTBP2 {ECO:0000313|EMBL:JAB33658.1};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB33658.1};
RN   [1] {ECO:0000313|EMBL:JAB33658.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Cerebral cortex {ECO:0000313|EMBL:JAB33658.1};
RX   PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA   Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA   Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT   "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT   sequences.";
RL   Gigascience 3:14-14(2014).
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DR   EMBL; GAMR01000274; JAB33658.1; -; mRNA.
DR   AlphaFoldDB; U3D5A3; -.
DR   SMR; U3D5A3; -.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   GO; GO:0043484; P:regulation of RNA splicing; IEA:UniProt.
DR   CDD; cd12778; RRM1_PTBP2; 1.
DR   CDD; cd12783; RRM2_PTBP2; 1.
DR   CDD; cd12696; RRM3_PTBP2; 1.
DR   Gene3D; 3.30.70.330; -; 4.
DR   InterPro; IPR006536; HnRNP-L/PTB.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR021790; PTBP1-like_RRM2.
DR   InterPro; IPR035002; PTBP2_RRM1.
DR   InterPro; IPR034799; PTBP2_RRM3.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR   PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR   PANTHER; PTHR15592:SF16; POLYPYRIMIDINE TRACT-BINDING PROTEIN 2; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   Pfam; PF13893; RRM_5; 1.
DR   Pfam; PF11835; RRM_8; 1.
DR   SMART; SM00360; RRM; 4.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 4.
DR   PROSITE; PS50102; RRM; 4.
PE   2: Evidence at transcript level;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176}.
FT   DOMAIN          59..133
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          181..257
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          338..412
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          455..530
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
SQ   SEQUENCE   532 AA;  57647 MW;  A77702A0B7A84298 CRC64;
     MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV
     LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH
     LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV
     LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG
     QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL
     LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG
     VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE
     GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG
     TVKAFKFFQR DHKMALLQMA TVEEAIQALI DLHNYNLGEN HHLRVSFSKS TI
//