ID U3DCA4_CALJA Unreviewed; 348 AA.
AC U3DCA4; F6TXG8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Integrin beta-1-binding protein 2 {ECO:0000313|EMBL:JAB36173.1};
DE SubName: Full=Integrin subunit beta 1 binding protein 2 {ECO:0000313|Ensembl:ENSCJAP00000024667.2};
GN Name=ITGB1BP2 {ECO:0000313|EMBL:JAB36173.1,
GN ECO:0000313|Ensembl:ENSCJAP00000024667.2};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB36173.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000024667.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB36173.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB02204.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB36173.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000024667.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; GAMT01009657; JAB02204.1; -; mRNA.
DR EMBL; GAMQ01005678; JAB36173.1; -; mRNA.
DR RefSeq; XP_002763027.2; XM_002762981.2.
DR Ensembl; ENSCJAT00000026088.3; ENSCJAP00000024667.2; ENSCJAG00000013429.4.
DR eggNOG; KOG1667; Eukaryota.
DR GeneTree; ENSGT00940000159429; -.
DR HOGENOM; CLU_040079_0_1_1; -.
DR OrthoDB; 1360344at2759; -.
DR TreeFam; TF105394; -.
DR Proteomes; UP000008225; Chromosome X.
DR Bgee; ENSCJAG00000013429; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd06488; p23_melusin_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 4.10.1130.20; -; 2.
DR InterPro; IPR007051; CHORD_dom.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR46983; CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46983:SF2; CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF04968; CHORD; 2.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51401; CHORD; 2.
DR PROSITE; PS51203; CS; 1.
PE 2: Evidence at transcript level;
KW Integrin {ECO:0000313|EMBL:JAB36173.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 5..64
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 150..209
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 216..305
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 320..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..348
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 348 AA; 38357 MW; 19B2980BA26A854C CRC64;
MSLLCRNKGC GQHFDPNTNL PDSCCHHPGV PIFHDALKGW SCCRKRTVDF SEFLNIKGCT
MGPHCAEKLP EAPQPEGPAT SSSLQEQKPL NVIPKSAETL HRERPKSELP LKLLPLNISQ
ALEMALEQKE LNQEPGAGLD SNLIRTGSSC QNPGCDAVYQ GPESDAAPCT YHPGAPRFHE
GMKSWSCCGI QTLDFGAFLA QPGCRVGRHD WGKQLPASCR HDWHQTDSLV VVTVYGQIPL
PAFNWVKASQ TELHVHIVFD GNRVFQAQMK LWGVINVEQS SVSLMPSRVE ISLVKVDPGS
WAQLEHPDAL AEKARAGVVL EMGEEESDDS DDDLSWTEEE EEEEAMGE
//
