ID U3E599_CALJA Unreviewed; 1354 AA.
AC U3E599;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Partitioning defective 3 homolog isoform 2 {ECO:0000313|EMBL:JAB37379.1};
GN Name=PARD3 {ECO:0000313|EMBL:JAB37379.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB37379.1};
RN [1] {ECO:0000313|EMBL:JAB37379.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAB37379.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Endomembrane system
CC {ECO:0000256|ARBA:ARBA00004308}.
CC -!- SIMILARITY: Belongs to the PAR3 family.
CC {ECO:0000256|ARBA:ARBA00005358}.
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DR EMBL; GAMQ01004472; JAB37379.1; -; mRNA.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 3.
DR Gene3D; 2.30.42.10; -; 3.
DR InterPro; IPR021922; Par3/HAL_N.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR16484:SF10; PARTITIONING DEFECTIVE 3 HOMOLOG; 1.
DR PANTHER; PTHR16484; PARTITIONING DEFECTIVE 3 RELATED; 1.
DR Pfam; PF12053; Par3_HAL_N_term; 1.
DR Pfam; PF00595; PDZ; 3.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR PROSITE; PS50106; PDZ; 3.
PE 2: Evidence at transcript level;
KW Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 271..347
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 461..546
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 590..665
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 81..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 863..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..1023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1127..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1047..1074
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 154..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 957..976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 977..1023
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1147..1176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1213..1265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1283..1298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1299..1313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1354 AA; 151261 MW; 0CD237F17CE14FAE CRC64;
MKVTVCFGRT RVVVPCGDGH MKVFSLIQQA VTRYRKAIAK DPNYWIQVHR LEHGDGGILD
LDDILCDVAD DKDRLVAVFD EQDPHHGGDG TSASSTGTQS PEIFGSELAT NSVSAFQPYQ
ATSEIEVTPS VLRANMPLHV RRSSDPALIG LSTSISDNNF SSEEPSRKNP TRWSTTAGFL
KQNTAGSPKT CDRKKDENYR SLPRDTSNWS NQFQRDNARS SLSASHPMVG KWLEKQEQDE
DGTEEDNSRV EPVGHADTGL ENIPNFSLDD MVKLVQVPND GGPLGIHVVP FSARGGRTLG
LLVKRLEKGG KAEHENLFHE NDCIVRINDG DLRNRRFEQA QHMFRQAMRL PIIWFHVVPA
ANKEQYEQLS QSEKNNYYSS RFSPDSQYID NRSVNSAGLH TVQRAPRLNH PPEQIDSHSR
LPHSVHPSGK PPSAPAPAPQ NVFSTTISSG YNTKKIGKRL NIQLKKGTEG LGFSITSRDI
TIGGSAPIYV KNILPRGAAI QDGRLKAGDR LIEVNGVDLA GKSQEEVVSL LRSTKMEGTV
SLLVFRQEDA FHPRELNAEP SQMQIPKETK TEDEDIVLTP DGTREFLTFE VPLNDSGSAG
LGVSVKGNRS KENHADLGIF VKSIINGGAA SKDGRLRVND QLIAVNGESL LGKTNQDAME
TLRRSMSTEG NKRGMIQLIV ARRISKCNEL KSPGSPPGPE LPIETALDDR ERRISHSLYS
GIEGLDESPS RNAALSRIMG KYQLSPTVNM PQDDTVIIED DRLPVLPPHL SDQSSSSSHD
DVGFVTTDAS TWAKAAISDS ADCSLSPDVD PVLAFQREGF GRQSMSEKRT KQFSDASQLD
FVKTRKSKSM DLGIADETKL STVDDQKAGG SPSRDVGPSL GLKKSSSLES LQTAVAEVTL
NGDIPFHRPR PRIIRGRGCN ESFRAAIDKS YDKPAVDDDD EGMETLEEDT EESSRSGRES
VSTASDQPSH SLERQMNGNQ EKGDKTDRKK DKTGKEKKKD RDKEKDKMKA KKGMLKGLGD
MFRFGKHRKD DKIEKTGKIK IQESFTSEEE RIRMKQEQER IQAKTREFRE RQARERDYAE
IQDFHRTFAC DDELMYGGVS SYEGSMALNA RPQSPREGHL MDALYAQVKK PRNSKPSPVD
SNRSTPSNHD RIQRLRQEFQ QAKQDEDVED RRRTYSFEQP WPNARPSAQS GRHSVSVEVQ
MQRQRQEERE SSQQAQRQYS SLPRQSRKNA SSVSQDSWEQ NYSPGEGFQS AKENPRYSSY
QGSRNGYLGG HGFNARVMLE TQELLRQEQR RKEQQMKKQA PSEGPSNYDS YKKVQDPSYA
PPKGPFRQDV PPSPSQVARL NRLQTPEKGR PFYS
//
