ID U3EHM2_CALJA Unreviewed; 276 AA.
AC U3EHM2; F7I339;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Syntaxin-12 {ECO:0000313|EMBL:JAB50398.1, ECO:0000313|Ensembl:ENSCJAP00000017205.3};
GN Name=STX12 {ECO:0000313|EMBL:JAB50398.1,
GN ECO:0000313|Ensembl:ENSCJAP00000017205.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB50398.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000017205.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB50398.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB09947.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB50398.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB29219.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB17570.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB37469.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000017205.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GAMT01001914; JAB09947.1; -; mRNA.
DR EMBL; GAMS01005566; JAB17570.1; -; mRNA.
DR EMBL; GAMR01004713; JAB29219.1; -; mRNA.
DR EMBL; GAMQ01004382; JAB37469.1; -; mRNA.
DR EMBL; GAMP01002357; JAB50398.1; -; mRNA.
DR RefSeq; XP_002750545.1; XM_002750499.4.
DR STRING; 9483.ENSCJAP00000017205; -.
DR Ensembl; ENSCJAT00000018197.4; ENSCJAP00000017205.3; ENSCJAG00000009378.5.
DR GeneID; 100392943; -.
DR KEGG; cjc:100392943; -.
DR CTD; 23673; -.
DR GeneTree; ENSGT01000000214440; -.
DR OMA; KWCLYLL; -.
DR OrthoDB; 200189at2759; -.
DR Proteomes; UP000008225; Chromosome 7.
DR Bgee; ENSCJAG00000009378; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0031083; C:BLOC-1 complex; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0045121; C:membrane raft; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045335; C:phagocytic vesicle; IEA:Ensembl.
DR GO; GO:0000407; C:phagophore assembly site; IEA:Ensembl.
DR GO; GO:0031201; C:SNARE complex; IEA:Ensembl.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0000045; P:autophagosome assembly; IEA:Ensembl.
DR GO; GO:0033344; P:cholesterol efflux; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd15876; SNARE_syntaxin12; 1.
DR CDD; cd00179; SynN; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 1.20.58.70; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR InterPro; IPR006011; Syntaxin_N.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; SYNTAXIN; 1.
DR PANTHER; PTHR19957:SF88; SYNTAXIN-12; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF14523; Syntaxin_2; 1.
DR SMART; SM00503; SynN; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 252..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 178..240
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT COILED 56..83
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 276 AA; 31612 MW; 9595502E74BC326D CRC64;
MSYGPLDMYR NPGPSGPQLR DFSSIIQTCS GNIQRISQAT AQIKNLMSQL GTKQDSTKLQ
ENLQQLQHST NQLAKETNEL LKELGSLPLP LSASEQRQQR LQKERLMNDF SAALNNFQAV
QRRVSEKEKE SIARARAGSR LSAEERQREE QLVSFDSHEE WNQMQSQEDE VAITEQDLEL
IKERETAIRQ LEADILDVNQ IFKDLAMMIH DQGDLIDSIE ANVESSEVHV ERATEQLQRA
AYYQKKSRKK MCILVLVLSV IVLILGLIIW LVYKTK
//
