ID U3EIW3_CALJA Unreviewed; 1229 AA.
AC U3EIW3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Multimerin-1 {ECO:0000313|EMBL:JAB21875.1};
GN Name=MMRN1 {ECO:0000313|EMBL:JAB21875.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB21875.1};
RN [1] {ECO:0000313|EMBL:JAB21875.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Hippocampus {ECO:0000313|EMBL:JAB21875.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GAMS01001261; JAB21875.1; -; mRNA.
DR AlphaFoldDB; U3EIW3; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048583; P:regulation of response to stimulus; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.60.120.40; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR PANTHER; PTHR15427:SF3; MULTIMERIN-1; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF07546; EMI; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS50871; C1Q; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS51041; EMI; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1229
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004640344"
FT DOMAIN 207..282
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 1042..1078
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1097..1229
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 69..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1068..1077
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1229 AA; 138487 MW; 4D5A1C9A9C243723 CRC64;
MKGARLFVLL SSLWSGGIGL NNSKHSWTIL DDGNSQKTTT SASVPSNKIQ RLQILPTTQV
MSAEIVTTPE ARTSEESLLK STLPPSETSA PAEGVRNQTL TSTEKAEEAV KFQNLTLPTK
SSTKFNPGAE SAVLSNSTLN FLQSFAGKSN EQATSLQAVG GDGGSGGVGG SGGTGNRGPR
ETYLSRGDSS PSRRTDYQKS SFETTRGKNW CAYVHTRLSP TVILDNQVSY VPGGRGPCGW
TSGSCPQRSQ RISNPIYRMQ HKIVTSLDWR CCPGYSGPKC QLKAQEQQHL IHTNQAESHT
AIGKGVAEQQ QQQDCGDPEV MQKMTDQMNY QAMKLTLLQK KIDNISLTVN DVRNIYSSLE
EKVSEDKGRE FQSFLKGLES KSINVLIRDI VKEQFNILQN DMQETVAQLF KTVSSISEDL
ESTRQIIQRV NESVVSVAAQ QKFVLMKENR PTLTDVVDLR NHIVNVRQEM TLTCEKPIKE
LEVKQAHLEG ALEQEHSRSI QYYESLNKTL SEMKEIHEQL LPTEKVSDQK NVPAAESVSN
NVTEYMSTLH ENIKKQSLMM LQMFDDLHIQ ESKINNLTIS LEMEKESLRG ECKDMLSKCR
NDFKFQLKDT EESLHVLNQT LAEVIFPMDN KMDKMSEQLN DLTYDMEILQ PLLEQGASLR
QTVIHEQPKE AVMTRKKIEN LTSAVNSLNF IIKELTKRHN LLRNEVQSRD DALERRISEY
ALEMEDGLNK TMTIVNNAID FIQDNYVLKE TLSTIKDNYE IHHKCPSNME TILTFIPQFQ
RLNDSIQILV NDNQRYNLVL QVAKTLAGFP RDEKLNQSNF QKMYQMFNET TSQMRKYQQT
VSHLEEKILS AIKISKTFET RLQDVESKVT QTLIPYYISL NKGSAVTNER DRVLQLQVLN
SRFKALEVKS IHLSINFSLL NKTLHEVLTM CHNASTSVSE LNATIPKWIK RYMPDIQLLQ
KGLTEFVESI IEIKTQAVLS NLTCCLDQSL PGSLANAKSQ KQAKSLLKKI NTLKKPTVNL
TTVLIGRTQR NTDNIIYPVT EEYSSCSRHP CQNGGTCING RTSFTCACRH PFTGDNCTIK
LVEENALAPD FSKGSYRYAP MVAFFASHTY GMTTPGPILF NNLDVNYGAS YTPRTGKFRI
PYLGVYVFKY TIESFSAHIS GFLVVDGIDK LAFESENIDS EIHCDRVLTG DALLELNYGQ
EVWLRLAKGT IPAKFPPVTT FSGYLLYRT
//
