ID U3EX26_CALJA Unreviewed; 2432 AA.
AC U3EX26;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Neuron navigator 2 isoform 1 {ECO:0000313|EMBL:JAB30341.1};
GN Name=NAV2 {ECO:0000313|EMBL:JAB30341.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB30341.1};
RN [1] {ECO:0000313|EMBL:JAB30341.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Cerebral cortex {ECO:0000313|EMBL:JAB30341.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- SIMILARITY: Belongs to the Nav/unc-53 family.
CC {ECO:0000256|ARBA:ARBA00006255}.
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DR EMBL; GAMR01003591; JAB30341.1; -; mRNA.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022008; P:neurogenesis; IEA:InterPro.
DR CDD; cd21285; CH_NAV2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR039041; Nav/unc-53.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12784:SF6; NEURON NAVIGATOR 2; 1.
DR PANTHER; PTHR12784; STEERIN; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00307; CH; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00033; CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50021; CH; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT DOMAIN 85..192
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 194..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 683..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 916..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1272..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1332..1389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1417..1437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1449..1537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1568..1603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1734..1831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1895..1929
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2368..2432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1630..1713
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 214..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..525
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..652
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 916..966
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..1024
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1025..1041
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1102..1125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1449..1467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1473..1489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1518..1537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1568..1597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1734..1762
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1763..1778
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1802..1831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1902..1929
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2399..2414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2432 AA; 261651 MW; D8817A226DD878E0 CRC64;
MPAILVASKM KSGLPKPVHS AAPILHVPPA RAGPQPCYLK LGSKVEVSKT TYPSQIPLKS
QVLQGLQEPA GEGLPLRKSG SVENGFDTQI YTDWANHYLA KSGHKRLIKD LQQDVTDGVL
LAQIIQVVAN EKIEDINGCP KNRSQMIENI DACLNFLAAK GINIQGLSAE EIRNGNLKAI
LGLFFSLSRY KQQQQQPQKQ HLSSPLPPAV SQVAGAPSQC QAGTPQQQVP AAPQAPCQPH
QPAPHQQSKA QAEMQSRLPG PTARVSAAGS EAKARGGSAT ANNRRSQSFN NYDKSKPVTS
PPPPPSSHEK EPLASSASSH PGMSDNAPAP LESSSSSTPT NCSTSSAIPQ PSAATKPWRS
KSLSVKHSAT VSMLSIKPAG PEAPRPTPEA MKPAPNNQKS MLEKLKLFNS KGGSKAGEGP
GSRDTSCERL ETLPSFEESE ELEATGRMLT TMGPVSSSPK IALKGIAQRT FSRALTNKKS
SPKGNEKEKE KQQREKDKEK SKDLAKRASV TERLDLKEEP KEDPSGTAMP EMPKKSSKIA
SFIPKGGKLN SAKKEPVAPS HSGIPKPGMK SMPGKSPSAP APSKEGERSR SGKLSSGLPQ
QKPQLDGRHS SSSSSLASSE GKGLGGTTLN HSISSQTVSG SVGTTQTTGS NTVSVQLPQP
QQQYNHPNTA TVAPFLYRSQ TDTEGNVTAE SSSTGVSMEP SHFTKTGQPA LEELTGEDPE
ARRLRTVKNI ADLRQNLEET MSSLRGTQVT HSTLETTFDT NVTTEMSGRS ILSLTGRPTP
LSWRLGQSSP RLQAGDAPSM GNGYPPRANA SRFINTESGR YVYSAPLRRQ LASRGSSICH
VDVSDKAGDE IDLEGISIDA PGYMSDGDVL SKNIRTDDIT SGYMTDGGLG LYTRRLNRLP
DGMAVVRETL QRNTSLGLGD ADSWDDSSSV SSGISDTIDN LSTDDINTSS SISSYANTPA
SSRKNLDVQT DAEKHSQVER NSLWSGDDVK KSDGGSDSGI KMEPGSKWRR NPSDVSDESD
KSTSGKKNPV ISQTGSWRRG MTAQVGITMP RTKPSAPAGA LKTPGTGKTD DAKVSEKGRL
SPKASQVKRS PSDAGRSSGD ESKKPLPSSS RTPTANANSF GFKKQSGSAA GLAMITASGA
TVTSRSATLG KIPKSSALVS RSAGRKSSMD GAQNQDDGYL SLSSRTNLQY RSLPRPSKSN
SRNGAGNRSS TSSIDSNISS KSAGLPVPKL REPSKTALGS SLPGLVNQTD KEKGISSDSE
SVASCNSVKV NPAAQPVSSP AQATLQPGAK YPDVASPTLR RLFGGKPTKQ VPIATAENMK
NSVVISNPHA TMTQQGNLDS PSGSGILSSG SSSPLYSKNV DLNQSPLASS PSSAHSGPSN
SLTWGTNASS SSAVSKDGLG FQSVSSLHTS CESIDISLSS GGGPSHNSST GLIASSKDDS
LTPFVRTNSV KTTLSESPLS SPAASPKFCR STLPRKQDSD PHLDRNTLPK KGLRYTPTSQ
LRTQEDAKEW LRSHSAGGLQ DTAANSPFSS GSSVTSPSGT RFNFSQLASP TTVTQMSLSN
PTMLRTHSLS NADGQYDPYT DSRFRNSSMS LDEKSRTMSR SGSFRDGFEE VHGSSLSLVS
STSSIYSTPE EKCQSEIRKL RRELDASQEK VSALTTQLTA NAHLVAAFEQ SLGNMTIRLQ
SLTMTAEQKD SELNELRKTI ELLKKQNAAA QAAINGVINT PELNCKGNGT AQSADLRIRR
QHSSDSVSSI NSATSHSSVG SNIESDSKKK KRKNWVNELR SSFKQAFGKK KSPKSASSHS
DIEEMTDSSL PSSPKLPHNG STGSTPLLRN SHSNSLISEC MDSEAETVMQ LRNELRDKEM
KLTDIRLEAL SSAHQLDQLR EAMNRMQSEI EKLKAENDRL KSESQGSGCS RAPSQVSISA
SPRQSMGLSQ HSLNLTESTS LDMLLDDTGE CSARKEGGRH VKIVVSFQEE MKWKEDSRPH
LFLIGCIGVS GKTKWDVLDG VVRRLFKEYI IHVDPVSQLG LNSDSVLGYS IGEVKRSNTS
ETPELLPCGY LVGENTTITV TVKGLAENSL DSLVFESLIP KPILQRYVSL LMEHRRIILS
GPSGTGKTYL ANRLSEYMVL REGRELTDGV IATFNVDHKS SKELRQYLSN LADQCNSENN
AVDMPLVIIL DNLHHVSSLG EIFNGLLNCK YHKCPYIIGT MNQATSSTPN LQLHHNFRWV
LCANHTEPVK GFLGRFLRRK LMETEISGRV RNMELVKIID WIPKVWHHLN RFLEAHSSSD
VTIGPRLFLS CPIDVDGSRV WFTDLWNYSI IPYLLEAVRE GLQLYGRRAP WEDPAKWVMD
TYPWAASPQQ HEWPPLLQLR PEDVGFDGYS VPREGSTSKQ VPPSDAEGDP LMNMLMRLQE
AANYSSPQSY DSDSNSNSHH DDILDSSLES TL
//
