ID U3FY57_CALJA Unreviewed; 266 AA.
AC U3FY57; F7IR71;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=AlkB homolog 6 {ECO:0000313|Ensembl:ENSCJAP00000080306.1};
DE SubName: Full=Putative alpha-ketoglutarate-dependent dioxygenase ABH6 isoform 2 {ECO:0000313|EMBL:JAB51855.1};
GN Name=ALKBH6 {ECO:0000313|EMBL:JAB51855.1,
GN ECO:0000313|Ensembl:ENSCJAP00000080306.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB51855.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000080306.1, ECO:0000313|Proteomes:UP000008225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB51855.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB05246.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB51855.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB37068.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000080306.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the alkB family.
CC {ECO:0000256|ARBA:ARBA00007879}.
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DR EMBL; GAMT01006615; JAB05246.1; -; mRNA.
DR EMBL; GAMQ01004783; JAB37068.1; -; mRNA.
DR EMBL; GAMP01000900; JAB51855.1; -; mRNA.
DR RefSeq; XP_002762079.1; XM_002762033.3.
DR STRING; 9483.ENSCJAP00000017890; -.
DR Ensembl; ENSCJAT00000126655.1; ENSCJAP00000080306.1; ENSCJAG00000072699.1.
DR GeneID; 100394712; -.
DR KEGG; cjc:100394712; -.
DR CTD; 84964; -.
DR GeneTree; ENSGT00510000048626; -.
DR HOGENOM; CLU_059836_2_0_1; -.
DR OMA; ILQDEMY; -.
DR OrthoDB; 169579at2759; -.
DR Proteomes; UP000008225; Chromosome 22.
DR Bgee; ENSCJAG00000043322; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005925; C:focal adhesion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032862; ALKBH6.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR46030; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6; 1.
DR PANTHER; PTHR46030:SF1; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 2: Evidence at transcript level;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000313|EMBL:JAB51855.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 124..255
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
FT REGION 167..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 266 AA; 29326 MW; 094018B56C4F8392 CRC64;
MAGRGMGMLN LEIGGDTGGR IGCEELVLME EQDARVPALE PFRVEQAPPI IYYVPDFISK
EEEEYLLRQV FNAPKPKWTQ LSGRKLQNWG GLPHPRGMVP ERLPPWLQRY VDKVSDLSLF
GGLPANHVLV NQYLPGEGIM PHEDGPLYYP TVSTISLGSH TVLDLYEPRR PEDDDPTEQP
RAPPRPTTSL LLEPRSLLVL RGPAYTRLLH GIAAARVDAL DAASPPPNAA ACQSARPGAC
LVRGTRISLT IRRVPRVLRA GLLLGK
//
