ID U3FZH9_MICFL Unreviewed; 325 AA.
AC U3FZH9;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Mitochondrial fission regulator {ECO:0000256|RuleBase:RU369053};
OS Micrurus fulvius (Eastern coral snake) (Coluber fulvius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Micrurus.
OX NCBI_TaxID=8637 {ECO:0000313|EMBL:JAB54215.1};
RN [1] {ECO:0000313|EMBL:JAB54215.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Venom gland {ECO:0000313|EMBL:JAB54215.1};
RX PubMed=23915248; DOI=10.1186/1471-2164-14-531;
RA Margres M.J., Aronow K., Loyacano J., Rokyta D.R.;
RT "The venom-gland transcriptome of the eastern coral snake (Micrurus
RT fulvius) reveals high venom complexity in the intragenomic evolution of
RT venoms.";
RL BMC Genomics 14:531-531(2013).
CC -!- FUNCTION: May play a role in mitochondrial aerobic respiration. May
CC also regulate mitochondrial organization and fission.
CC {ECO:0000256|ARBA:ARBA00037378}.
CC -!- FUNCTION: Plays a role in mitochondrial aerobic respiration. Regulates
CC mitochondrial organization and fission.
CC {ECO:0000256|RuleBase:RU369053}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173,
CC ECO:0000256|RuleBase:RU369053}.
CC -!- SIMILARITY: Belongs to the MTFR1 family.
CC {ECO:0000256|ARBA:ARBA00005807, ECO:0000256|RuleBase:RU369053}.
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DR EMBL; GAEP01000606; JAB54215.1; -; mRNA.
DR AlphaFoldDB; U3FZH9; -.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0009060; P:aerobic respiration; IEA:UniProtKB-UniRule.
DR GO; GO:0000266; P:mitochondrial fission; IEA:UniProtKB-UniRule.
DR InterPro; IPR007972; Mtfr1.
DR PANTHER; PTHR14215:SF1; MITOCHONDRIAL FISSION REGULATOR 1; 1.
DR PANTHER; PTHR14215; PROTEIN OF UNKNOWN FUNCTION DUF729; 1.
DR Pfam; PF05308; Mito_fiss_reg; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion {ECO:0000256|RuleBase:RU369053};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..325
FT /note="Mitochondrial fission regulator"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004641242"
FT REGION 105..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..139
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 36057 MW; EFD56F5BC41F63D5 CRC64;
MICWIKHLFR VIFMQVGLTM ESLLWSNKTY GPNRSIVRKI GSNLSLIQCP RVQFQLTSQP
AESTQSNQLK EDAVVSLVDV GWVAEEDDEG DKVFTRFRSE GWSKSQPFLK SEGSSGRDSS
TEELLPKKSQ EMEDSKNTVA KNDEALQKIN ALENELANLR AQIAKIVSLQ EQNLAAAGIC
SSAPLSVVPP PPPPPLPPPS PLQQSVSAID LIKERKGKRI NSGKTLIDGD PKKLEMPNML
DILKDMNNVK LRSVRRPEES TIRKTADPTD PAAVIAEALK KKFAYRYRSD SSSESDKQIS
TSETSLFGPH LLKPTGKMKN LIENC
//
