GenomeNet

Database: UniProt
Entry: U3IZ50_ANAPL
LinkDB: U3IZ50_ANAPL
Original site: U3IZ50_ANAPL 
ID   U3IZ50_ANAPL            Unreviewed;       713 AA.
AC   U3IZ50;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   25-OCT-2017, entry version 33.
DE   SubName: Full=Hyperpolarization activated cyclic nucleotide gated potassium channel 3 {ECO:0000313|Ensembl:ENSAPLP00000012526};
GN   Name=HCN3 {ECO:0000313|Ensembl:ENSAPLP00000012526};
OS   Anas platyrhynchos (Mallard) (Anas boschas).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anas.
OX   NCBI_TaxID=8839 {ECO:0000313|Ensembl:ENSAPLP00000012526, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000012526}
RP   NUCLEOTIDE SEQUENCE.
RA   Li N.;
RT   "The genome sequence and transcriptome of duck provide insight into
RT   the interaction host.";
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000012526}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23749191; DOI=10.1038/ng.2657;
RA   Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H.,
RA   Gan S., Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q.,
RA   Fairley S., Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A.,
RA   Lee T., Kim K.W., Sheng Z., An Y., Searle S., Herrero J.,
RA   Groenen M.A., Crooijmans R.P., Faraut T., Cai Q., Webster R.G.,
RA   Aldridge J.R., Warren W.C., Bartschat S., Kehr S., Marz M.,
RA   Stadler P.F., Smith J., Kraus R.H., Zhao Y., Ren L., Fei J.,
RA   Morisson M., Kaiser P., Griffin D.K., Rao M., Pitel F., Wang J.,
RA   Li N.;
RT   "The duck genome and transcriptome provide insight into an avian
RT   influenza virus reservoir species.";
RL   Nat. Genet. 45:776-783(2013).
RN   [3] {ECO:0000313|Ensembl:ENSAPLP00000012526}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2013) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSAPLP00000012526}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; ADON01092859; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADON01092860; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSAPLT00000013268; ENSAPLP00000012526; ENSAPLG00000012747.
DR   GeneTree; ENSGT00900000140801; -.
DR   OMA; VMEQHLV; -.
DR   OrthoDB; EOG091G0JQU; -.
DR   Proteomes; UP000016666; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:Ensembl.
DR   GO; GO:0030552; F:cAMP binding; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR030173; HCN4.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR10217:SF375; PTHR10217:SF375; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000016666};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00502630, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM      6     26       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    233    258       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      336    442       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
SQ   SEQUENCE   713 AA;  80683 MW;  29CC696DE197E5F2 CRC64;
     RFYWDLIMLL LMVGNLIILP VGITFFKDEN TPPWIVFNVL SDTFFLADLV LNFRTGIVVE
     DNTEIILDPH TIKMKYLKSW FLVDFISSIP VDYIFLIVDL ETQVDSDVYK TARALRIVRF
     TKILSLLRLL RLSRLIRYIH QWEEIFHMTY DLASAVVRIF NLIGMMLLLC HWDGCLQFLV
     PMLQDFPEDC WVSINHMVND SWGKQYSHAL FKAMSHMLCI GYGQQAPEGM TDVWLTMLSM
     IVGATCYAMF IGHATALIQS LDSSRRQYQE KYKQVEQYMS FHKLPGDTRQ RIHEYYEHRY
     QGKMFDEENI LGELSEPLKE EIINFNCRNL VANMPLFANA DPNFVTAMLT KLRFEVFQPG
     DFIIREGTVG KKMYFIQHGV VSILTKGNKE TKLSDGSYFG EICLLTRGRR TASVRADTYC
     RLYSLSVDNF NEVLEEYPMM RRAFETVAMD RLDRIGKKNS ILLRKRAEHS SGPMNNEMIQ
     QIVKHDQDVA HNIQELQQMT MGRELSGKPV IWEPLVHAPL QTAAATTNVA IALTHQHSLQ
     AHIFLPPSSI SSPLSPEATL LTKQVRRSQP SLGGSRPSSV SSPSGAQSHL QTPAAAPRFR
     KVSRATGSHI SLLMQPQQLV KHRSIQGLPV GRLTQDVRLL SASQPSLPNK VAQQADGSSL
     QQGRKSVGNL ARRSSPSVAG LLAKPCRAQV PGARSPLPEV PAATLGAQCW ALV
//
DBGET integrated database retrieval system