ID U3JDH1_FICAL Unreviewed; 625 AA.
AC U3JDH1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Serine/threonine protein phosphatase 2A regulatory subunit {ECO:0000256|PIRNR:PIRNR028043};
GN Name=PPP2R5D {ECO:0000313|Ensembl:ENSFALP00000000825.1};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000000825.1, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000000825.1, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000000825.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the phosphatase 2A regulatory subunit B56
CC family. {ECO:0000256|ARBA:ARBA00009745}.
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DR AlphaFoldDB; U3JDH1; -.
DR STRING; 59894.ENSFALP00000000825; -.
DR Ensembl; ENSFALT00000000829.2; ENSFALP00000000825.1; ENSFALG00000000797.2.
DR eggNOG; KOG2085; Eukaryota.
DR GeneTree; ENSGT01030000234620; -.
DR HOGENOM; CLU_012437_3_2_1; -.
DR OMA; DGTEDNQ; -.
DR Proteomes; UP000016665; Chromosome 3.
DR GO; GO:0000159; C:protein phosphatase type 2A complex; IEA:UniProtKB-UniRule.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:Ensembl.
DR GO; GO:0019888; F:protein phosphatase regulator activity; IEA:UniProtKB-UniRule.
DR GO; GO:0035307; P:positive regulation of protein dephosphorylation; IEA:Ensembl.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002554; PP2A_B56.
DR PANTHER; PTHR10257; SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B; 1.
DR PANTHER; PTHR10257:SF89; SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT DELTA ISOFORM; 1.
DR Pfam; PF01603; B56; 1.
DR PIRSF; PIRSF028043; PP2A_B56; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665}.
FT REGION 22..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 72471 MW; 8B3B8B6242B23BD6 CRC64;
MTQRKDNRNQ DLSLLLGILW SASDCQESPK STKSTTKPGG SSSSSSGKDG GAENSEEAQQ
PQQQLQQSQQ QTQQQPTSNK RPSNSAPPPT QLNKIKYSGG PQIVKKERRH SSSRFNLSKN
RELQKLPALK DAPPHEREEL FIQKLRQCCV LFDFISDPLS DLKFKEVKRA GLNEMVEYIT
HNRDVVTEAI YPEAVIMFSV NLFRTLPPSS NPTGAEFDPE EDEPTLEAAW PHLQLVYEFF
LRFLESPDFQ PNVAKKYIDQ KFVLSLLDLF DSEDPRERDF LKTILHRIYG KFLGLRAYVR
RQINNIFYRF IYETEHHNGI AELLEILGSI INGFALPLKE EHKMFLIRVL LPLHKVKSLS
VYHPQLAYCV VQFLEKDSSL TEPVIVGLLK FWPKTHSPKE VMFLNELEEI LDVIEPSEFV
KVMEPLFRQL AKCVSSPHFQ VAERALYYWN NEYIMSLISD NAAKILPIMF PALYKNSKSH
WNKTIHGLIY NALKLFMEMN QKLFDDCTQQ YKAEKQKGRF RMKEREEMWQ KIEELARLNP
QYPMYYAPLP LPSVCCMETE TPTAEDIQLL KKTVETEAVQ MLKDLKKDKV LLRRKSELPQ
DVYTIKALEA HKRAEEFLTS SQEAL
//
