ID U3JJ52_FICAL Unreviewed; 956 AA.
AC U3JJ52;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=WD repeat domain 47 {ECO:0000313|Ensembl:ENSFALP00000002806.2};
GN Name=WDR47 {ECO:0000313|Ensembl:ENSFALP00000002806.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000002806.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000002806.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000002806.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005050540.1; XM_005050483.2.
DR STRING; 59894.ENSFALP00000002806; -.
DR Ensembl; ENSFALT00000002818.2; ENSFALP00000002806.2; ENSFALG00000002692.2.
DR Ensembl; ENSFALT00000038795.1; ENSFALP00000020558.1; ENSFALG00000002692.2.
DR GeneID; 101811586; -.
DR KEGG; fab:101811586; -.
DR CTD; 22911; -.
DR eggNOG; KOG0641; Eukaryota.
DR GeneTree; ENSGT00940000155561; -.
DR HOGENOM; CLU_014985_0_0_1; -.
DR OrthoDB; 76273at2759; -.
DR Proteomes; UP000016665; Chromosome 8.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0030425; C:dendrite; IEA:Ensembl.
DR GO; GO:0030426; C:growth cone; IEA:Ensembl.
DR GO; GO:0005874; C:microtubule; IEA:Ensembl.
DR GO; GO:0043025; C:neuronal cell body; IEA:Ensembl.
DR GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR GO; GO:0021960; P:anterior commissure morphogenesis; IEA:Ensembl.
DR GO; GO:0006914; P:autophagy; IEA:Ensembl.
DR GO; GO:0021801; P:cerebral cortex radial glia-guided migration; IEA:Ensembl.
DR GO; GO:0022038; P:corpus callosum development; IEA:Ensembl.
DR GO; GO:0120168; P:detection of hot stimulus involved in thermoception; IEA:Ensembl.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0061744; P:motor behavior; IEA:Ensembl.
DR GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:Ensembl.
DR GO; GO:0061351; P:neural precursor cell proliferation; IEA:Ensembl.
DR GO; GO:0097150; P:neuronal stem cell population maintenance; IEA:Ensembl.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040067; WDR47.
DR PANTHER; PTHR19863; NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG; 1.
DR PANTHER; PTHR19863:SF5; WD REPEAT-CONTAINING PROTEIN 47; 1.
DR Pfam; PF17814; LisH_TPL; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 82..139
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT REPEAT 694..724
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 788..828
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 833..874
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 875..909
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 921..956
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 408..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 956 AA; 106116 MW; 6F829E454D9AA2FC CRC64;
MRGAVNRGGC CKPGGAGCRM ESRVERKNML EQRGAAIMTA EETVNVKEAE IIKLILDFLN
SRKLHISMLA LEKESGVING LFSDDMLFLR QLILDGQWDE VLQFIQPLEC MEKFDKKRFR
YIIMKQKFLE ALCVNNAMSA EDEPQHLEFT MREAVQCLHA LEEYCPSKED YSKLCLLLTL
PRLTNHAEFK DWNPSTARVH CFEEACVMVA EFIPADRKLS EAGFKASNNR LFQLVMKGLL
YECCVEFCQS KATGEEITES EVLLGIDLLC GNGCDDLDLS LLSWLQNLPA TVFSCAFEQK
MLNIHVDKLL KPTKAAYADL LTPLISKLSP YPSSPMRRPQ SADAYMTRSL NPALDGLSCG
LTNHDKRVTD LGTKTSPMSH SFANFHYPGV QNLSRSLMLE NTECHSIFEE SPERDTPVEP
QHPIGSETAC QSSAPENELN PAQSQGSAKQ EKNELRDSTE QFQEYYRQRL RYQQHLEQKE
QQRQLYQQML LEGGVHQEEG ADQQQNLTEQ FLNRSIQKLG ELNMGMDSLG NDVQTLSQQC
NGSKGIVSTH PASNFTSAPS DGSQRITTDS PNLNTSTPRK CGSANQIPFP EESPVQGSQS
SASEHAVSQP QSEESSGNLS RTRGDEDDKS KKQFICINTL EDTQAVRAVA FHPSGSLYAV
GSNSKTLRVC AYPEVIDPSA YNTPKQPVVR FKRNKHHKGS IYCVAWSPCG QLLATGSNDK
YVKVLPFNAE TCNATGPDLE FSMHDGTIRD LAFMEGPESG GAILISAGAG DCNIYTTDCQ
RGQGLHALSG HTGHILALYT WSGWMIASGS QDKTVRFWDL RVPSCVRVVG TTFHGTGSAV
ASVAVDPSGR LLATGQEDSS CMLYDIRGGR MVQSYHPHGS DVRSVRFSPG AHYLLTGSYD
MKIKVTDLQG DLTKQLPLMV VGEHKDKVIQ CRWHTQDLSF LSSSADRTVT LWTYNG
//
